385 Results for "

cortex

" in MedChemExpress (MCE) Product Catalog:
Products (385)

385 Results for "cortex" in MCE Product Catalog:

Cat. No.: HY-107339R
CAS No.: 131-01-1
Synonyms: Harmonyl (Standard)
Deserpidine (Standard) is the analytical standard of Deserpidine. This product is intended for research and analytical applications. Deserpidine (Harmonyl) is an alkaloid isolated from the root of Rauwolfia canescens related to Reserpine. Deserpidine is used as an antihypertensive agent and a tranquilizer. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex .
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Cat. No.: HY-106874B
CAS No.: 119813-87-5
Synonyms: rel-RS-15385-197
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

rel-Delequamine (rel-RS-15385-197) is an orally active, brain-penetrant, potent and selective M2-adrenoceptor antagonist and α2-adrenoceptor antagonist. rel-Delequamine has a pKi of 9.45 for α2-adrenoceptors in the rat cortex. rel-Delequamine augments K +-evoked release of noradrenaline with an EC50 of 1 nM .
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Cat. No.: HY-17416S2
Guanfacine- 13C,d5 hydrochloride is the deuterium and 13C labeled Guanfacine hydrochloride (HY-17416). Guanfacine hydrochloride is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD) .
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Cat. No.: HY-17416AS1
Guanfacine- 15N3, 13C2 is 15N and 13C labeled Guanfacine (HY-17416A). Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD) .
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Cat. No.: HY-N2414R
CAS No.: 514-39-6
Periplogenin (Standard) is the analytical standard of Periplogenin (HY-N2414). Periplogenin is an orally active cardiac glycoside found in Cortex periplocae. Periplogenin can induce ROS production and necroptosis and cause G0/G1 phase arrest. Periplogenin can inhibit pyroptosis by regulating the NLRP3/Caspase-1/GSDMD signaling. Periplogenin suppresses growth of prostate carcinoma cells by docking to an ATP1A1 protein pocket and forming a hydrogen bond with T804. Periplogenin can be used for the researches of cancer, inflammation and immunology, such as prostate carcinoma, rheumatoid arthritis and psoriasis .
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Cat. No.: HY-N3330
CAS No.: 93697-42-8
Magnolignan C is a lignan, that can be isolated from Magnoliae Cortex .
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Cat. No.: HY-W194842
CAS No.: 525-41-7
Harmalan is a tryptamine binding site stimulant and an imidazoline binding site ligand. Harmalan can be isolated from the leaves of Flindersia laevicarpa. Harmalan elevates 5-HT (HY-B1473A) levels and reduces 5-HIAA levels in the cerebral cortex. Harmalan increases spontaneous motor activity, induces clonic convulsions, produces anxiogenic effects, and elicits head weaving, hindlimb abduction, trunk curvature, piloerection, resting tremor, ataxia, forelimb abduction with increased muscle tone, and occasional alternating forepaw treading behaviors .
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Cat. No.: HY-129706
CAS No.: 57184-68-6
Target:  

Others

Research Areas:  

Cardiovascular Disease

LY127210 free base is an orally active peripheral arterial vasodilating antihypertensive agent. LY127210 free base interferes with the baroreflex mechanism, exerts direct myocardial bradycardic activity, has no α or β receptor blocking properties, and acts via all conventional administration routes. LY127210 free base reduces vascular resistance, cardiac output, heart rate, left ventricular end-diastolic pressure, regional vascular resistance, as well as blood flow in the skin and cerebral cortex. LY127210 free base can be used in research related to hypertension .
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Cat. No.: HY-P1558B
CAS No.: 79190-56-0
Synonyms: Adrenocorticotropic Hormone (11-24) hexaacetate
Target:  

Endogenous Metabolite

Research Areas:  

Others

ACTH (11-24) (hexaacetate) is a type of adrenocorticotropic hormone that can trigger cortisol secretion in bovine adrenal cortex cells .
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Cat. No.: HY-116738
CAS No.: 616-68-2
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Trimecaine, a local neural blockade agent, has a strong depressant effect on the cerebral cortex and the ascending reticular formation of the brain stem .
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Cat. No.: HY-P1588
CAS No.: 112748-19-3
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.
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Cat. No.: HY-W701984
CAS No.: 739-26-4
Research Areas:  

Endocrinology

11β-Hydroxyetiocholanolone is a metabolite of Hydrocortisone (HY-N0583). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
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Cat. No.: HY-N8550
CAS No.: 516-42-7
Synonyms: α-Cortolone
Cortolone (α-Cortolone) is a metabolite of the glucocorticoid cortisol (Hydrocortisone (HY-N0583)). Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
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Cat. No.: HY-NP0209
Hydrocortisone-OVA is a conjugate of Hydrocortisone (HY-N0583) and OVA peptide. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .
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Cat. No.: HY-120302
CAS No.: 149027-97-4
Research Areas:  

Metabolic Disease

PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively .
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Cat. No.: HY-136800
CAS No.: 78664-73-0
Research Areas:  

Endocrinology

Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens, and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems .
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Cat. No.: HY-103114
CAS No.: 190508-50-0
AT1015 hydrochloride is a potent antagonist of 5-HT2 receptor, with the pKi of 7.94. AT1015 inhibits vasoconstriction and blocks platelet aggregation .
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Cat. No.: HY-100481
CAS No.: 139088-45-2
Synonyms: RPR101048
Research Areas:  

Neurological Disease

RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors .
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Cat. No.: HY-N20394
Synonyms: Pseudolarix amabilis cortex extract
Category:  

Extract

Target:  

Fungal

Cortex pseudolaricis extract (Pseudolarix amabilis cortex extract) is a root bark extract of Pseudolarix amabilis Rehder, which has antifungal and anticancer biological activities.
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Cat. No.: HY-N21289
Target:  

Others

Cortex phellodendri polysaccharide is a polysaccharide derived from Cortex phellodendri.
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