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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
385 Results for "
cortex
" in MedChemExpress (MCE) Product Catalog:
Products (385)
385 Results for "cortex" in MCE Product Catalog:
Art. -Nr.: HY-N0473S5
CAS. Nr.: 81201-90-3
Art. -Nr.: HY-N0473S7
CAS. Nr.: 81201-89-0
Art. -Nr.: HY-P3883
CAS. Nr.: 81381-50-2
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Art. -Nr.: HY-14547
CAS. Nr.: 350992-10-8
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Bifeprunox is a potent dopamine D2-like and 5-HT1A receptor partial agonist with pKis of 7.19 and 8.83 for cortex 5-HT1A and striatum D2, and a pEC50 of 6.37 for hippocampus 5-HT1A, respectively. Bifeprunox is an antipsychotic for the research of schizophrenia .
Art. -Nr.: HY-N2158
CAS. Nr.: 31002-12-7
Category:
Liliaceae Xanthones Other Diseases Phenols Polyphenols Anemarrhena asphodeloides Bunge Plants Disease Research Fields
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Art. -Nr.: HY-N6803
CAS. Nr.: 857859-82-6
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Trihexyphenidyl is a selective and orally active M1 muscarinic receptor antagonist with an IC50 of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl can be used for the research of Parkinson's disease. .
Art. -Nr.: HY-P10278
CAS. Nr.: 133658-45-4
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Art. -Nr.: HY-N0473S12
CAS. Nr.: 104931-15-9
Art. -Nr.: HY-W794785
CAS. Nr.: 633304-27-5
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WAY 208466 is a selective 5-HT6 receptor agonist with an EC50 of 7.3 nM. WAY-208466 increases GABA levels following both acute and chronic administration in the dorsolateral frontal cortex of rat models with stereotaxic surgery. WAY 208466 can be used for anxiety-related disorders like obsessive compulsive disorder (OCD) research .
Art. -Nr.: HY-120016
CAS. Nr.: 136959-96-1
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RU 43044 is an orally active, selective glucocorticoid receptor inhibitor. RU 43044 blocks glucocorticoid receptor activity and reverses the enhanced dopamine release induced by high potassium in the prefrontal cortex. RU 43044 also inhibits thymocyte receptor down-regulation induced by high-dose glucocorticoids without affecting thymocyte apoptosis or basal receptor expression. RU 43044 is widely applicable to research related to depression .
Art. -Nr.: HY-17416R
CAS. Nr.: 29110-48-3
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Guanfacine (hydrochloride) (Standard) is the analytical standard of Guanfacine (hydrochloride). This product is intended for research and analytical applications. Guanfacine hydrochloride is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD) .
Art. -Nr.: HY-129810
CAS. Nr.: 130325-35-8
Synonyms: CAM 1028
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PD 135158 (CAM 1028) is a selective CCKB receptor antagonist with an IC50 of 2.8 nM against mouse cortex CCKB. PD 135158 shows anxiolytic activity .
Art. -Nr.: HY-W686963
CAS. Nr.: 7146-60-3
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Art. -Nr.: HY-130325
CAS. Nr.: 73477-53-9
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α-Guanidinoglutaric acid is a guanidino compound first found in cobaltinduced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric acid induces epileptic seizures in rats after intraventricular administration .
Art. -Nr.: HY-107563
CAS. Nr.: 184576-87-2
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ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access .
Art. -Nr.: HY-107563A
CAS. Nr.: 1781941-93-2
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ROS 234 dioxalate is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 dioxalate diaplays poor central access .
Art. -Nr.: HY-N15712
CAS. Nr.: 138591-13-6
Category:
Magnoliaceae Houpoea officinalis (Rehder & E. H. Wilson) N. H. Xia & C. Y. Wu Phenols Polyphenols Plants
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Art. -Nr.: HY-18138
CAS. Nr.: 1400811-63-3
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PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. PF-03382792 produces moderate increases in cortical Ach in the rat prefrontal cortex .
Art. -Nr.: HY-107339A
CAS. Nr.: 6033-69-8
Synonyms: Harmonyl hydrochloride
Forschungsgebiete:
Deserpidine hydrochloride (Harmonyl hydrochloride) is an antihypertensive compound that competitively inhibits the activity of angiotensin converting enzyme (ACE). Deserpidine hydrochloride competes with angiotensin I for ACE, preventing the conversion of angiotensin I to angiotensin II, thereby lowering blood pressure. Deserpidine hydrochloride can also reduce angiotensin II-induced aldosterone secretion from the adrenal cortex .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
