141 Results for "

envelope

" in MedChemExpress (MCE) Product Catalog:
Products (141)

141 Results for "envelope" in MCE Product Catalog:

Cat. No.: HY-178135
CAS No.: 2409183-70-4
Research Areas:  

Infection

SCR005 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR005 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR005 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR005 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR005 can be used for the study and prevention of enveloped virus pandemics .
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Cat. No.: HY-178137
CAS No.: 2409183-72-6
Research Areas:  

Infection

SCR007 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR007 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR007 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR007 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR007 can be used for the study and prevention of enveloped virus pandemics .
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Cat. No.: HY-P11733
Target:  

Bacterial

Research Areas:  

Infection

(KFF)3K-acpP is an antibacterial agent conjugating of cell penetrating peptide (KFF)3K (HY-P10556) and acpP
peptide nucleic acid. (KFF)3K-acpP binds to the translation start site region of acpP mRNA, sterically blocking ribosome binding and inhibiting translation of the acyl carrier protein. (KFF)3K-acpP induces bacterial envelope stress response pathways, and triggers depletion of outer membrane protein F (ompF) transcript. (KFF)3K-acpP can be used for the research of infections .
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Cat. No.: HY-184852
CAS No.: 151-41-7
Synonyms: Dodecyl hydrogen sulphate; Dodecyl sulfate
Lauryl sulfate (Dodecyl hydrogen sulphate) is an anionic chaotropic surfactant. Lauryl sulfate dissolves viral envelopes, denatures viral proteins, inhibits viral infectivity and HIV-1 syncytium formation. Lauryl sulfate potently inhibits the infectivity of HSV-1 strain F (ED50 = 17.9 μM) and HSV-2 strain 333 (ED50 = 32.7 μM). Lauryl sulfate induces environmental toxicity, disrupting environmental balance and physiological processes of organisms. As a contaminant, Lauryl sulfate is toxic to aquatic and terrestrial organisms. Lauryl sulfate can be used in studies related to sexually transmitted infections .
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Cat. No.: HY-P74184
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His Tag); HCV-1a E2 Protein
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P74185
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His Tag); HCV-1a E2 Protein
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-187669
CAS No.: 56799-51-0
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Obtusilactone is a butyrolactone compound that is first isolated and extracted from Lindera obtusiloba. Obtusilactone can be used in cancer research .
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Cat. No.: HY-Y0788R
CAS No.: 496-15-1
Indoline (Standard) is an analytical standard for Indoline (HY-Y0788). This product is intended for research and analytical applications. Indoline is a HIV-1 envelope glycoprotein gp120 binder. Indoline binds to the conserved CD4-binding site of gp120 (the Phe 43 cavity and its surrounding vestibule), competitively blocks the binding of CD4, and prematurely triggers conformational changes of the Env trimer, resulting in viral inactivation. Indoline induces the conformational opening of HIV-1 Env on infected cells, exposes vulnerable epitopes, increases antibody recognition rate, enhances the binding of FcγRIIIa receptors, and sensitizes infected cells to antibody-dependent cellular cytotoxicity. Indoline is a derivative of Indole (HY-W001132). Indoline can be used in studies related to HIV-1 infection .
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Cat. No.: HY-P74883
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: envelope glycoprotein gp160; Env polyprotein; Surface protein gp120; SU; Glycoprotein 120; gp120; Transmembrane protein gp41; TM; Glycoprotein 41; gp41 ; env
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P74884
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: envelope glycoprotein gp160; Env polyprotein; Surface protein gp120; SU; Glycoprotein 120; gp120; Transmembrane protein gp41; TM; Glycoprotein 41; gp41 ; env
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P705392
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: envelope glycoprotein gp160; Env polyprotein; Surface protein gp120; SU; Glycoprotein 120; gp120; Transmembrane protein gp41; TM; Glycoprotein 41; gp41 ; env
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-183314
Target:  

Flavivirus

Research Areas:  

Infection

ZIKV-IN-9 is a ZIKV inhibitor that blocks the early binding of viral particles to the cell surface. ZIKV-IN-9 inhibits ZIKV in various cell models. ZIKV-IN-9 is applicable to research related to Zika virus infection .
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Cat. No.: HY-P810459
Synonyms: SYNE3, Spectrin Repeat Containing Nuclear envelope Family Member 3, Nesprin-3, LINC00341, NET53, Long Intergenic Non-Protein Coding RNA 341, Nuclear envelope Spectrin Repeat Protein 3, KASH Domain-Containing Protein 3, NCRNA00341, C14orf139, FLJ25605, C14orf49, Nesp3, KASH3, Chromosome 14 Open Reading Frame 139, Chromosome 14 Open Reading Frame 49, Uncharacterized Protein C14orf113, Non-Protein Coding RNA 341, C14ORF139, NESPRIN-3, C14ORF49, NESP3

Host:  

Rabbit

Application:  

WB, FC, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-14805S
CAS No.: 2923753-84-6
Purity:  99.14%
Synonyms: ST-246-d4
Tecovirimat-d4 (ST-246-d4) is a deuterium-labelled Tecovirimat (HY-14805). Tecovirimat is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat could be used in the study for orthopoxvirus-induced diseases .
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Cat. No.: HY-W322225
CAS No.: 59752-57-7
Synonyms: DLPE; 1,2-Dilauroyl-sn-glycero-3-PE
Target:  

Liposome

Research Areas:  

Others

1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) is an anionic phospholipid. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine promotes the endocytosis of liposome-DNA complexes into target cells, and subsequently mediates membrane fusion between liposome carriers and endosomes to deliver DNA into the nucleus. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a component of anionic artificial viral envelope liposomes, which deliver plasmid DNA to hepatoma cells without serum inhibition. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine enables the construction of biocompatible non-viral gene delivery vector systems. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is applicable for liposome synthesis .
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Cat. No.: HY-183416
CAS No.: 111234-77-6
Research Areas:  

Others

M&B 39279 is an inhibitor of protoporphyrinogen oxidase (Protoporphyrinogen Oxidase). M&B 39279 induces protoporphyrin IX accumulation, light-dependent lipid peroxidation, degradation of membranes and organelles, and reduction of photosynthesis. M&B 39279 functions through the mechanism of action of diphenyl ether herbicides, and can be used for studies on PPO inhibition and herbicide mechanisms of action .
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Cat. No.: HY-N20707
CAS No.: 24312-00-3
Castalagin is an orally active natural product with multiple biological activities including antibacterial activity against bacteria and anti-leishmanial activity against Leishmania aethiopica. Castalagin exhibits inhibitory activity against PARP1 and DNA topoisomerase II, with an IC50 of 0.86 μM for bovine PARP1. Castalagin reduces poly (ADP-ribosyl) ation modification in cells. Castalagin binds to the cell envelope of Ruminococcus bromii, increases the ratio of CD8+/FOXP3+CD4+ T cells in the tumor microenvironment, and acts as a prebiotic to enhance the activity of anti-PD-1 therapy. Castalagin induces morphological changes in Leishmania aethiopica promastigotes and inhibits their proliferation. Castalagin inhibits PBP2a-mediated peptidoglycan layer stabilization, disrupts bacterial peptidoglycan assembly, and inhibits and disintegrates bacterial biofilms. Castalagin can be used in research related to diseases such as cancer, leishmaniasis, and bacterial infections .
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Cat. No.: HY-187035
CAS No.: 868066-26-6
Target:  

CDK STAT

Research Areas:  

Cancer

SNX631 is an orally active and selective CDK8/CDK19 inhibitor. SNX631 reduces the phosphorylation of STAT1/STAT3 S727, and upregulates miR-21-5p, miR-21-3p and miR-221 in cancer cells. SNX631 transcription-independently inhibits meiotic resumption in mouse oocytes, blocks nuclear envelope breakdown, first polar body extrusion and mitochondrial expansion and aggregation, with no cytotoxicity. SNX631, in combination with Lapatinib (HY-50898) or Trastuzumab (HY-P9907), synergistically inhibits cancer cell growth, upregulates the tumor suppressor BTG2, prevents Lapatinib-induced upregulation of oncogenic miRNAs, overcomes drug resistance, reduces the infiltration of αSMA+ stromal fibroblasts and ARG1+ M2 macrophages, and exhibits favorable biosafety. SNX631 can be used in studies related to HER2-positive breast cancer and cancer .
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Cat. No.: HY-P72263
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUP210; Nuclear Pore Membrane Glycoprotein 210; Nucleoporin 210; Pore Membrane Protein Of 210 KDa; POM210; Nuclear Pore Protein Gp210; KIAA0906; Nucleoporin 210kDa; GP210; Nucleoporin Nup210; Nuclear envelope Pore Membrane Protein POM 210; FLJ22389
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P77109
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUP210; Nuclear Pore Membrane Glycoprotein 210; Nucleoporin 210; Pore Membrane Protein Of 210 KDa; POM210; Nuclear Pore Protein Gp210; KIAA0906; Nucleoporin 210kDa; GP210; Nucleoporin Nup210; Nuclear envelope Pore Membrane Protein POM 210; FLJ22389
Species:  
Human
Source:  
Sf9 insect cells
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