164 Results for "

anionic

" in MedChemExpress (MCE) Product Catalog:
Products (164)

164 Results for "anionic" in MCE Product Catalog:

Cat. No.: HY-Y0504S
CAS No.: 2483824-12-8
Trimethylammonium chloride- 13C3,d9 is the 13C3,d9-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-Y0504S1
CAS No.: 107766-37-0
Synonyms: Hegzadesil-d10; Trimethylamine hydrochloric acid-d10; Trimethylamine monohydrochloride-d10
Trimethylammonium chloride-d10 (Hegzadesil-d10) is the d10-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-Y0504S2
CAS No.: 108451-51-0
Synonyms: Hegzadesil-15N; Trimethylamine hydrochloric acid-15N; Trimethylamine monohydrochloride-15N
Trimethylammonium chloride- 15N (Hegzadesil- 15N) is the 15N-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-Y0504S3
CAS No.: 18856-86-5
Trimethylammonium chloride-d9 is the d9-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-Y0504S4
CAS No.: 347840-14-6
Synonyms: Hegzadesil-d6; Trimethylamine hydrochloric acid-d6; Trimethylamine monohydrochloride-d6
Trimethylammonium chloride-d6 (Hegzadesil-d6) is the d6-labeled Trimethylammonium chloride (HY-Y0504). Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase .
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Cat. No.: HY-112307A
CAS No.: 124011-52-5
Purity:  99.97%
Target:  

Liposome

(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be studied for drug delivery and the synthesis of liposomes. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-containing liposomes can induce Tregs that are specific for the liposomes’ cargo. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is taken up by antigen-presenting cells mediated via complement component 1q (C1q) .
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Cat. No.: HY-W284558S
CAS No.: 2708287-31-2
Sodium hexadecyl sulfate-d33 is the deuterium labeled Sodium hexadecyl sulfate. Sodium hexadecyl sulfate is a long-chain anionic surfactant. Sodium hexadecyl sulfate can act as an interface-regulating substance to form a soft layer on the surface of carbon nanotubes, guide proteins to adsorb in the correct orientation with active sites facing outward through electrostatic interactions, and significantly enhance the activity of immobilized enzymes. Sodium hexadecyl sulfate can replace or supplement SDS (HY-Y0316) in capillary gel electrophoresis (CGE) .
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Cat. No.: HY-142991
CAS No.: 185435-28-3
Synonyms: POPG
Target:  

Liposome

Research Areas:  

Others

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .
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Cat. No.: HY-W714524A
CAS No.: 40290-44-6
Synonyms: 16:0-18:1 PS (POPS) free acid
Target:  

Liposome

Research Areas:  

Others

2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine (16:0-18:1 PS (POPS) free acid) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes .
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Cat. No.: HY-178736S
Synonyms: DLPE-d46; 1,2-Dilauroyl-sn-glycero-3-PE-d46
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine-d46 (DLPE-d46; 1,2-Dilauroyl-sn-glycero-3-PE-d46) is the deuterium labeled 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) is an anionic phospholipid. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine promotes the endocytosis of liposome-DNA complexes into target cells, and subsequently mediates membrane fusion between liposome carriers and endosomes to deliver DNA into the nucleus. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a component of anionic artificial viral envelope liposomes, which deliver plasmid DNA to hepatoma cells without serum inhibition. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine enables the construction of biocompatible non-viral gene delivery vector systems. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is applicable for liposome synthesis .
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Cat. No.: HY-148601
CAS No.: 217939-97-4
Synonyms: DSPG
Target:  

Liposome

Research Areas:  

Inflammation/Immunology

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) is an anionic (negatively charged) phospholipid . 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is used to prepare lipid microbubbles as ultrasound contrast agents. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol can be used to construct liposomes as vaccine carriers for the treatment of atherosclerosis. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is applicable to the research of drug delivery and diagnostic preparations .
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Cat. No.: HY-163746
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

BuChE-IN-11 (Compound 3b-1) is an selective BuChE inhibitor with an IC50 of 0.44 μM for hBuChE. BuChE-IN-11 has high blood-brain barrier permeability and exhibits strong antioxidant activity due to its free radical scavenging properties. BuChE-IN-11 interacts with the choline binding site, acetyl binding site, and peripheral anionic site, exhibiting submicromolar BuChE inhibitory activity and preventing β-amyloid (Aβ) self-aggregation. BuChE-IN-11 holds promise for research in the field of Alzheimer's disease .
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Cat. No.: HY-D1739
Research Areas:  

Others

DDAO phosphate diTEA is an amphoteric surfactant derived from DDAO (dimethyldodecylamine oxide). The head group of DDAO in DDAO phosphate diTEA exists in a non-ionic state at pH > 7 and in a cationic state at pH < 5 due to protonation of the oxygen atom. When combined with the anionic surfactant SDS, DDAO can incorporate into mixed micelles, reducing the net micellar charge and attenuating electrostatic repulsion between SDS head groups. DDAO can be used to formulate the ONOO⁻-targeting probe DDAO-PN, which generates significant near-infrared fluorescence at 657 nm .
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Cat. No.: HY-N6711
CAS No.: 57749-43-6
Equisetin is an N-methylserine-derived acyl tetramic acid, quorum sensing inhibitor (QSI), herbicides and antibiotics. Equisetin specifically inhibits the anionic carriers of substrates in the inner mitochondrial membrane. Equisetin inhibits the activity of HIV-1 integrase, 11β-HSD1, and 2,4-dinitrophenol (Dnp)-stimulated ATPase (IC50 = ~8 nmol per mg of protein). Equisetin exhibits growth inhibition of bacteria, anti-inflammatory, amelioration of lipid-associated disorders, and cytotoxic effects .
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Cat. No.: HY-DY2020
Target:  

Fluorescent Dye

Research Areas:  

Others

Neutral Red Staining Solution (for Live Cells) is a vital stain used for vital staining of peripheral blood cells, and it can also be used for staining other living cells or tissues. Neutral Red Staining Solution (for Live Cells) accumulates in cytoplasmic vacuoles, lysosomes of living cells, as well as plant/fungal vacuoles. It binds to anionic sites, suberin, lignin, cell walls, DNA and phenolic substances, and can intercalate into DNA. Neutral Red Staining Solution (for Live Cells) stains the cytoplasm of specific phytoplankton and estuarine zooplankton, while dead cells are not stained, enabling viability determination of such organisms .
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Cat. No.: HY-P5284
CAS No.: 1613231-49-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

RALA peptide is a cationic amphiphilic delivery agent targeting cell membranes, which forms nanoparticles through electrostatic interactions with anionic drugs. RALA peptide has pH-responsive binding properties, which can enhance the α-helical conformation in an acidic environment and destroy the endosomal membrane, promote the release of drugs into the cytoplasm, and exert efficient intracellular delivery activity. RALA peptide can be used in cancer research (enhancing the activity of bisphosphonates against prostate cancer and breast cancer cells) and bone tissue engineering (promoting osteoblast collagen deposition and extracellular matrix mineralization) .
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Cat. No.: HY-W096997S
CAS No.: 1219802-16-0
Synonyms: Sodium capryl sulfate-d17
Sodium octyl sulfate (SOS)-d17 (Sodium capryl sulfate-d17) is the deuterated analogue of Sodium octyl sulfate (SOS). Sodium octyl sulfate (Sodium capryl sulfate; SOS) is a medium‑chain anionic surfactant. Sodium octyl sulfate (SOS) can undergo strong hydrophobic interactions with serum albumins (such as human serum albumin (HSA) and bovine serum albumin (BSA)), while exhibiting weak interactions with other proteins including myoglobin and hemoglobin. As an environmental pollutant in freshwater ecosystems, Sodium octyl sulfate (SOS) can mimic interspecific pheromones released by Daphnia magna and induce the formation of multicellular colonies in green algae.
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Cat. No.: HY-N21596
CAS No.: 142878-03-3
Toddacoumaquinone is a coumarin-naphthoquinone dimer found in the roots of Toddalia asiatica. Toddacoumaquinone inhibits acetylcholinesterase (AChE) and β-amyloid (Aβ1-42) aggregation, with an IC50 of 46 μM against electric eel acetylcholinesterase. Toddacoumaquinone exerts antiviral effects against herpes simplex virus type 1 and herpes simplex virus type 2 (HSV). Toddacoumaquinone is used in research related to Alzheimer's disease and herpesvirus infections .
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Cat. No.: HY-W133963
CAS No.: 9063-38-1
Carboxyl methylstarch sodium is an anionic polymer prepared by carboxymethylation of starch, with properties of stability, thickening ability and film-forming capacity . Carboxyl methylstarch sodium exhibits metal adsorption activity and can remove copper ions and cadmium ions from aqueous solutions. Carboxyl methylstarch sodium can serve as a hydrophilic shell component for AIE-active luminescent polymer nanoprobes to achieve high water dispersibility. Carboxyl methylstarch sodium can bind to vancomycin without altering the in vitro antibacterial activity of vancomycin. Carboxyl methylstarch sodium possesses biodegradable, non-toxic and environmentally friendly characteristics. Carboxyl methylstarch sodium can be applied to relevant researches in various fields such as food, medicine and industry .
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Cat. No.: HY-119292
CAS No.: 553681-56-4
Research Areas:  

Neurological Disease

AP2238 is a dual-function acetylcholinesterase (AChE) inhibitor with Ki values for human AChE (HuAChE) and butyrylcholinesterase (BuChE) of 21.7 and 48.9 μM respectively. AP2238 blocks the pro-fibrotic interaction between the peripheral site of AChE and , and can inhibit Aβ aggregation. AP2238 can be used for the research of Alzheimer's disease .
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