2 Results for "

[3H]SCH 23390

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "[3H]SCH 23390" in MCE Product Catalog:

Cat. No.: HY-N15270
CAS No.: 93767-29-4
Synonyms: Secantioquine
S-Secoantioquine (Secantioquine) is a bisbenzylisoquinoline alkaloid secoderivative. In the rat striate membrane experiment, S-Secoantioquine shows weak displacement activity on 3H-SCH 23390 binding site, and certain displacement activity on 3H-raclopride binding site .
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Cat. No.: HY-165450
CAS No.: 125341-24-4
NNC-112 is a dopamine D1 receptor antagonist with a Ki of 0.18 nM for rat D1R and a Ki of 18 nM for 5-HT2. NNC-112 competitively inhibits [ 3H]SCH 23390 binding and blocks dopamine-stimulated adenylate cyclase. NNC-112 blocks D1 receptor-mediated rotational behavior in 6-OHDA-lesioned rats. NNC-112 can serve as a C11-labeled radioligand ([11C] NNC 112) for positron emission tomography imaging. NNC-112 can be used for research on schizophrenia and hypertension .
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