3 Results for "

AS269

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "AS269" in MCE Product Catalog:

Cat. No.: HY-128968
CAS No.: 1415246-35-3
Purity:  99.83%
Synonyms: Amberstatin; AS269
PEG4-aminooxy-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4 .
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Cat. No.: HY-147248
Synonyms: pAF-AS269
Target:  

EGFR

Research Areas:  

Cancer

Opadotina is a small molecule of anvatabart opadotin. Opadotina shows antineoplastic activity .
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Cat. No.: HY-P991930

Research Areas:  

Cancer

ARX305 Antibody is a high-affinity, humanized anti-CD70 antibody. ARX305 Antibody forms an antibody-drug conjugate (ADC) (ARX305) with the potent microtubule inhibitor PEG4-aminooxy-MMAF (AS269) (HY-128968). As a targeting component, ARX305 Antibody mediates the binding and internalization of ARX305 to CD70-positive tumor cells, whereas the unconjugated ARX305 Antibody exhibits only weak anti-tumor activity in various xenograft and disseminated tumor models. ARX305 Antibody can be used in the research of a variety of solid tumors and hematological malignancies .
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