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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
MPD
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "MPD" in MCE Product Catalog:
1
Research Areas:
Hexylene glycol is a low molecular weight surfactant with antimicrobial properties. Hexylene glycol is widely used in industrial chemicals and cosmetics .
Cat. No.: HY-162464
MPD2 is a Cereblon (CRBN) ligand and SARS-CoV-2 M Pro degrader with an IC50 <1000 nM against SARS-CoV-2 MPro[1]. MPD2 engages CRBN to mediate ubiquitination and proteasomal degradation of SARS-CoV-2 MPro, reducing SARS-CoV-2 MPro protein levels in infected cells . MPD2 inhibits viral replication of various SARS-CoV-2 strains and acts against nirmatrelvir-resistant SARS-CoV-2 viruses . MPD2 can be used for the research of covid-19 and for fighting against drug-resistant viral variants. .
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Hexylene glycol (Standard) is the analytical standard of Hexylene glycol. This product is intended for research and analytical applications. Hexylene glycol is a low molecular weight surfactant that is widely used as an industrial coating solvent without causing adverse health or environmental effects.
Cat. No.: HY-175294
CAS No.: 3054043-85-2
Target:
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PD-L1/Nampt-IN-1 is an orally active inhibitor that simultaneously target PD-L1 and NAMPT (nicotinamide phosphoribosyltransferase) with IC50s value of 63 nM and 582 nM. PD-L1/Nampt-IN-1 demonstrates cross-species affinity with comparable KD values for hPD-L1 (52.6 nM) and mPD-L1 (49.1 nM), respectively. PD-L1/Nampt-IN-1 effectively inhibits tumor growth by activating the tumor immune microenvironment. PD-L1/Nampt-IN-1 can be used for the study of melanoma .
Cat. No.: HY-RS08856
Target:
Research Areas:
MVD Human Pre-designed siRNA Set A contains three designed siRNAs for MVD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183866
CAS No.: 1911555-88-8
Synonyms: Maleimide-KGDEVD-doxorubicin
Target:
Research Areas:
MPD-1 (Maleimide-KGDEVD-doxorubicin) is a peptide drug conjugate (PDC). MPD-1 releases Doxorubicin (HY-15142) via radiation-activated caspase-3 cleavage, triggering a cytotoxic amplification cascade at the tumor site. MPD-1 enhances CD8 + T cell tumor infiltration, and activates antigen-presenting cells. MPD-1 enables dual-trigger payload release, amplifies cytotoxicity via in situ feedback, and selectively delivers payload to tumor microenvironments via enhanced albumin metabolism and macropinocytosis. MPD-1 exhibits antitumor efficacy in mouse colorectal cancer models. MPD-1 can be used for the research of colorectal cancer .
Cat. No.: HY-178097
HPK1-IN-62 is a selective and orally active HPK-1 inhibitor with an IC50 of 1.22 nM. HPK1-IN-62 significantly improves GLK selectivity (> 665-fold) and LCK selectivity (> 1095-fold). HPK1-IN-62 enhances T-cell activation and demonstrated synergistic effects when combined with anti-mPD-1 therapy in the MC38 tumor model, inhibiting a tumor growth. HPK1-IN-62 can be used in the researchs of colon cancer and cancer immunotherapy .
Cat. No.: HY-B1091B
Synonyms: MPD/BSA
Cat. No.: HY-RS18453
Target:
Research Areas:
Mvd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mvd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-B0903S
CAS No.: 284474-72-2
Synonyms: 2-Methyl-2,4-pentanediol-d12; MPD-d12
Cat. No.: HY-P704841
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Programmed cell death protein 1; PD-1; CD279; Pdcd1; MPD-1
Cat. No.: HY-P87094
Synonyms: Beta myosin heavy chain antibody; cardiac muscle beta isoform antibody; CMD1S antibody; CMH1 antibody; MPD1 antibody; MYH7 antibody; MYH7_HUMAN antibody; Myhc slow antibody; MyHC-beta antibody; MyHC-slow antibody; Beta myosin heavy chain antibody; cardiac muscle beta isoform antibody; CMD1S antibody; CMH1 antibody; MPD1 antibody; MYH7 antibody; MYH7_HUMAN antibody; Myhc slow antibody; MyHC-beta antibody; MyHC-slow antibody; MYHCB antibody; Myopathy, distal 1 antibody; Myosin heavy chain (AA 1-96) antibody; Myosin heavy chain 7 antibody; Myosin heavy chain antibody; Myosin heavy chain slow isoform antibody; Myosin heavy chain, cardiac muscle beta isoform antibody; Myosin, heavy chain 7, cardiac muscle, beta antibody; Myosin, heavy polypeptide 7, cardiac muscle, beta antibody; Myosin-7 antibody; Rhabdomyosarcoma antigen MU RMS 40.7A antibody; SPMD antibody; SPMM antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
