1 Result for "

6TI

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "6TI" in MCE Product Catalog:

Cat. No.: HY-128671
CAS No.: 574-25-4
Purity:  98.08%
Synonyms: 6TI; 6-Mercaptopurine riboside
Target:  

PPAR LXR JNK NO Synthase

Research Areas:  

Metabolic Disease

6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction .
loading...
    loading...