Search Result

Results for "

ABTS radicals

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Akt (3) AMPK (1) Amylases (3) AP-1 (2) Autophagy (2) Bacterial (4) Cholinesterase (ChE) (2) COX (2) Cytochrome P450 (1) DNA/RNA Synthesis (2) Drug Derivative (3) EGFR (1) Endogenous Metabolite (2) Environmental Pollutants (1) Estrogen Receptor/ERR (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (1) Fungal (3) Glycosidase (5) HMG-CoA Reductase (HMGCR) (1) HSP (1) IFNAR (1) Interleukin Related (1) LDLR (1) MMP (2) Monoamine Oxidase (1) NO Synthase (2) PD-1/PD-L1 (2) PPAR (1) Ras (2) Reactive Oxygen Species (ROS) (13) Reference Standards (2) STAT (2) Tim3 (2) TNF Receptor (2) Toll-like Receptor (TLR) (1) Tyrosinase (5) Wnt (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (2) Infection (5) Inflammation/Immunology (28) Metabolic Disease (12) Neurological Disease (11)

By Targets:

Acetyl-CoA Carboxylase (1)

Akt (3)

AMPK (1)

Amylases (3)

AP-1 (2)

Autophagy (2)

Bacterial (4)

Cholinesterase (ChE) (2)

COX (2)

Cytochrome P450 (1)

DNA/RNA Synthesis (2)

Drug Derivative (3)

EGFR (1)

Endogenous Metabolite (2)

Environmental Pollutants (1)

Estrogen Receptor/ERR (1)

Fatty Acid Synthase (FASN) (1)

Ferroptosis (1)

Fungal (3)

Glycosidase (5)

HMG-CoA Reductase (HMGCR) (1)

HSP (1)

IFNAR (1)

Interleukin Related (1)

LDLR (1)

MMP (2)

Monoamine Oxidase (1)

NO Synthase (2)

PD-1/PD-L1 (2)

PPAR (1)

Ras (2)

Reactive Oxygen Species (ROS) (13)

Reference Standards (2)

STAT (2)

Tim3 (2)

TNF Receptor (2)

Toll-like Receptor (TLR) (1)

Tyrosinase (5)

Wnt (2)

Xanthine Oxidase (1)

By Research Areas:

Cancer (10)

Cardiovascular Disease (2)

Infection (5)

Inflammation/Immunology (28)

Metabolic Disease (12)

Neurological Disease (11)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0828

Pterostilbene 5+ Cited Publications	Autophagy	Inflammation/Immunology Cancer
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-W047187

Lavandoside	Xanthine Oxidase NO Synthase TNF Receptor	Others
Lavandoside is an ABTS ^?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC₅₀ of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .

HY-N7005

Clitorin	EGFR Cytochrome P450 Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase HMG-CoA Reductase (HMGCR) PPAR AMPK	Metabolic Disease Inflammation/Immunology Cancer
Clitorin is an orally active flavonoid compound that can be isolated from Carica papaya. Clitorin is an inhibitor of EGFR (IC₅₀: 89.58 nM) and aromatase (IC₅₀: 77.41 nM). Clitorin has antioxidant and anti-tumor activities. In the DPPH and ABTS radical scavenging assays, Clitorin has IC₅₀ values of 91.96 ppm and 250.45 ppm, respectively. In addition, Clitorin can regulate lipogenesis and fatty acid oxidation and can be used in the research of non-alcoholic fatty liver disease .

HY-N0627

Kaempferol-7-O-β-D-glucopyranoside	LDLR	Others
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu ²⁺-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .

HY-N8220

2-(2-Phenylethyl)chromone Flidersiachromone	Glycosidase	Neurological Disease Cancer
2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS· ⁺ free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases .

HY-N2907

Atranorin	Wnt Ras Endogenous Metabolite Bacterial Fungal PD-1/PD-L1 Tim3 Akt AP-1 STAT	Infection Neurological Disease Inflammation/Immunology Cancer
Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC₅₀ values for scavenging DPPH and *ABTS* free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .

HY-N7627

Regaloside C	Estrogen Receptor/ERR Toll-like Receptor (TLR) Akt MMP HSP	Inflammation/Immunology
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges *ABTS* and DPPH free radicals. Regaloside C targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4 and HSP90-α. Regaloside C is applicable to research related to inflammatory diseases .

HY-N7607

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside	Reactive Oxygen Species (ROS)	Cardiovascular Disease
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid glycoside with antioxidant activity and free radical scavenging activity. Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside can scavenge free radicals such as ABTS+ and can be used in the study of antioxidant-related diseases (such as cardiovascular diseases and neurodegenerative diseases) .

HY-N0435

Isorhamnetin 3-gentiobioside	DNA/RNA Synthesis	Cancer
Isorhamnetin 3-gentiobioside is a flavonoid with activity of promoting cancer cell proliferation. Isorhamnetin 3-gentiobioside is an activator of DNA synthesis in MCF-7 human breast cancer cells with an EC₅₀ of 3.1 μg/mL. Isorhamnetin 3-gentiobioside exhibits ABTS radical scavenging activity with an IC₅₀ of 33.43 μg/mL. The compound can be used to study the bidirectional regulatory mechanism of cancer .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-W101585

Isoamyl benzoate Isopentyl benzoate	Environmental Pollutants	Inflammation/Immunology
Isoamyl benzoate (Isopentyl benzoate) is a natural aromatic ester compound. Isoamyl benzoate exhibits free radical scavenging capabilities against DPPH and ABTS, with its IC₅₀ values being 9.55 μg/mL and 7455.54 μM TE/g respectively. Isoamyl benzoate can be used in antioxidant research .

HY-N5130

Effusol	Others	Neurological Disease
Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC₅₀ values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline .

HY-N0828R

Pterostilbene (Standard)	Reference Standards Autophagy	Inflammation/Immunology Cancer
Pterostilbene (Standard) is the analytical standard of Pterostilbene. This product is intended for research and analytical applications. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-W018643A

(E)-Ferulic acid methyl ester Methyl (E)-ferulate	COX	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-149008

α-Amylase-IN-3	Amylases Cholinesterase (ChE)	Inflammation/Immunology
α-Amylase-IN-3 (Compound 4) is the inhibitor for α-Amylase, AChE and AChE with IC₅₀s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease .

HY-N8955

Maritimein	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Maritimein is an aurone glucoside and antioxidant with free radical scavenger activity, found in Coreopsis tinctoria Nutt.Maritimein scavenges ABTS•+ radical cations .

HY-178935

α-Amylase-IN-14	Amylases Reactive Oxygen Species (ROS)	Metabolic Disease Inflammation/Immunology
α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an α-amylase inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes .

HY-N2907R

Atranorin (Standard)	Wnt Reference Standards Ras Endogenous Metabolite Bacterial Fungal PD-1/PD-L1 Tim3 Akt AP-1 STAT	Infection Neurological Disease Inflammation/Immunology Cancer
Atranorin (Standard) is the analytical standard of Atranorin (HY-N2907). This product is intended for research and analytical applications. Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC₅₀ values for scavenging DPPH and *ABTS* free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .

HY-W207699

MAO-B-IN-46	Monoamine Oxidase Amylases	Neurological Disease Metabolic Disease Inflammation/Immunology
MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor (IC₅₀: 26.8 nM), with weak activity against hMAO-A (IC₅₀: 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor (IC₅₀: 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and *ABTS* free radicals, with IC₅₀ values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance .

HY-149670

Ferroptosis-IN-3	Ferroptosis	Inflammation/Immunology
Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC₅₀: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC₅₀: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation .

HY-P5318

MDYYFEER	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Others	Metabolic Disease
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-146172

Antioxidant agent-3	Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent *DPPH radicals* scavenging** activity and ABTS ⁺ scavenging activity with IC₅₀s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H₂O₂-treated HepG2 cells .

HY-N12291

7,4'-Dihydroxyhomoisoflavane	Others	Others
7,4'-Dihydroxyhomoisoflavane is a natural antioxidant. 7,4'-Dihydroxyhomoisoflavane has ABTS radical-scavenging capacity with an IC₅₀ of 0.22 mg/mL .

HY-157124

Tyrosinase-IN-19	Tyrosinase	Metabolic Disease
Tyrosinase-IN-19 (compound 9) is a competitive tyrosinase inhibitor. Tyrosinase-IN-19 has strong antioxidant activities against ROS, ABTS+, and DPPH radicals. Tyrosinase-IN-19 suppresses tyrosinase expression in a dose-dependent manner .

HY-N8254

Haginin A	Others	Others
Haginin A (compound 3）can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC₅₀ *values of 9.0 μM and 37.7 μM in the ABTS* system and DPPH system, respectively .**

HY-157123

Tyrosinase-IN-18	Tyrosinase	Metabolic Disease
Tyrosinase-IN-18 (compound 6) is a potent tyrosinase inhibitor. Tyrosinase-IN-18 inhibits melanogenesis in B16F10 mammalian cells. Tyrosinase-IN-18 has strong antioxidant activities against ROS, ABTS ⁺, and DPPH radicals .

HY-156711

Ternatumoside II	IFNAR	Inflammation/Immunology
Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC₅₀s: 260.5 μM and 320.2 μM for DPPH and ABTS) .

HY-172604

Neuroprotective agent 10	TNF Receptor Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology
Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective agent. Neuroprotective agent 10 scavenges ABTS radicals (scavenging IC₅₀: 9.20 μM), DPPH radicals (scavenging IC₅₀: 7.09 μM) and superoxide anion radicals (inhibition percentage: 48.4%). Neuroprotective agent 10 also alleviates H₂O₂-induced oxidative damage and LPS-induced neuroinflammation with antiepileptic activity. Neuroprotective agent 10 is promising for research of epilepsy and neuroprotection .

HY-N11771

Glyurallin B	Reactive Oxygen Species (ROS)	Others
Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS ⁺ radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC₅₀ values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .

HY-176437

Tyrosinase-IN-42	Tyrosinase	Metabolic Disease
Tyrosinase-IN-42 (Compound 13t) is a tyrosinase inhibitor (IC₅₀: 1.363 µM). Tyrosinase-IN-42 exhibits anti-browning effects on fresh-cut apples. Tyrosinase-IN-42 has antioxidant activity by scavenging DPPH and ABTS free radicals (IC₅₀: 57.90 and 45.64 µM, respectively) .

HY-168957

RuDiOBn	MMP Reactive Oxygen Species (ROS)	Others
RuDiOBn scanvages DPPH and ABTS free radicals (13.2% and 5.9% clearance at 100 μg/mL), exhibits low antioxidant activity. RuDiOBn inhibits the collagen glycation, reduces the formation of advanced glycation end products (AGEs) with an IC₅₀ of 2.45 μg/mL. RuDiOBn enhances the proliferation and migration of fibroblasts, stimulates the synthesis of collagen, promoting the skin repair and regeneration. RuDiOBn also inhibits collagenase .

HY-168501

Neuroprotective agent 6	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Neuroprotective Agent 6 (Compound Y12) is a neuroprotective agent with antioxidant activity and capabilities in DPPH, ABTS radical scavenging. Neuroprotective Agent 6 demonstrates superior neuroprotective effects in both cellular models induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and animal models induced by transient middle cerebral artery occlusion (tMCAO). Additionally, Neuroprotective Agent 6 exhibits significant metal chelating activity towards Cu ²⁺ .

HY-N19783

Carambolaside M	Drug Derivative	Others
Carambolaside M acts as an ABTS radical cation scavenger. Carambolaside M scavenges ABTS radical cations. Carambolaside M is isolated from the fresh sweet fruits of Averrhoa carambola L., a plant belonging to the genus Averrhoa in the Oxalidaceae family .

HY-N18281

Hazelnutin F	Drug Derivative	Inflammation/Immunology
Hazelnutin F is an indoleacetic acid glycoside found in the kernels of Corylus avellana L.. Hazelnutin F lacks significant antioxidant activity against ABTS and DPPH radicals .

HY-N17925

Falandioside B	Glycosidase	Metabolic Disease
Falandioside B is an α-glucosidase inhibitor with an IC₅₀ of 107.52 μM. Falandioside B scavenges ABTS radical cations. Falandioside B is applicable to research related to postprandial hyperglycemia .

HY-181253

α-Glucosidase-IN-111	Glycosidase	Metabolic Disease
α-Glucosidase-IN-111 (Compound 5d) is an α-glucosidase (α-Glucosidase) inhibitor with a IC₅₀ of 34.99 μg/mL. α-Glucosidase-IN-111 effectively scavenges DPPH free radicals and ABTS free radicals, with IC₅₀ values of 5.33 and 5.84 μg/mL, respectively. α-Glucosidase-IN-111 can be used in the research of type 2 diabetes .

HY-N9229

Myricadenin A	NO Synthase Bacterial	Infection Inflammation/Immunology
Myricadenin A is an iNOS inhibitor, capable of effectively inhibiting the production of NO (EC₅₀ = 18.1 μM). Myricadenin A has moderate ABTS free radical scavenging activity (SC₅₀ = 175.4 μM) and relatively weak anti-tuberculosis activity (MIC = 80.0 μg/mL). Myricadenin A can be used in inflammation-related research .

HY-N17733

4,5-O-Dicaffeoylquinic acid ethyl ester	Others	Metabolic Disease
4,5-O-Dicaffeoylquinic acid ethyl ester is an *ABTS* free radical scavenger with an IC₅₀ of 5.95 μM. 4,5-O-Dicaffeoylquinic acid ethyl ester shows no antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. 4,5-O-Dicaffeoylquinic acid ethyl ester can be used in liver injury protection studies .

HY-183792

Antibacterial agent 347	Bacterial Reactive Oxygen Species (ROS)	Infection
Antibacterial agent 347 (Compound 4d) is an Antibacterial agent. Antibacterial agent 347 exhibits selective antibacterial activity against Streptococcus mutans. Antibacterial agent 347 shows moderate ABTS• ⁺ free radical scavenging activity .

HY-182333

AChE-IN-112	Cholinesterase (ChE)	Neurological Disease
AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC₅₀ of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease .

HY-P11646

Brazzein	COX	Metabolic Disease Inflammation/Immunology
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC₅₀ of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC₅₀ = 12.55 μM) . Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation .

HY-181069

Neuroprotective agent 16	Reactive Oxygen Species (ROS) DNA/RNA Synthesis Interleukin Related	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Neuroprotective agent 16 is a blood-brain barrier-permeable neuroprotective agent. Neuroprotective agent 16 effectively scavenges DPPH and ABTS radicals, with IC₅₀ values of 7.98 μM and 5.50 μM, respectively. Neuroprotective agent 16 exhibits anti-inflammatory, antioxidant, and DNA damage-reducing activities. Neuroprotective agent 16 can be used in research on diseases such as ischemic stroke .

HY-169406

α-Glucosidase-IN-76	Glycosidase	Cancer
α-Glucosidase-IN-76 (Compound 4r) is an inhibitor for α-glucosidase with an IC₅₀ of 5.44 μM. α-Glucosidase-IN-76 scavenges ABTS+ free radicals with a TEAC value of 0.49. α-Glucosidase-IN-76 inhibits the proliferation of T24 bladder cancer cell with IC₅₀ of 1.74 μM .

HY-N16424

Methyl (Z)-ferulate Me cis-ferulate; cis-Ferulic acid methyl ester	Fungal	Infection
Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS ⁺ radical .

HY-181353

α-Glucosidase-IN-112	Glycosidase	Metabolic Disease Cancer
α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC₅₀ of 2.03 μM and a K_i of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS ⁺ free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer .

HY-181029

Tyrosinase-IN-49	Tyrosinase	Neurological Disease Inflammation/Immunology
Tyrosinase-IN-49 (Compound 12) is a potent and mixed-type chalcone-based tyrosinase inhibitor with an IC₅₀ of 0.19 μM. Tyrosinase-IN-49 has potent antioxidant potential with significant DPPH and ABTS radical scavenging capacity. Tyrosinase-IN-49 can chelate the binuclear copper ions in the active center of tyrosinase and reduce Cu ²⁺ to Cu ⁺, thereby reducing the catalytic activity of the enzyme. Tyrosinase-IN-49 has low cytotoxicity for HEK293 cells and zebrafish embryo. Tyrosinase-IN-49 shows antibrowning effects to improve food quality and can be used for research of food preservation .

HY-181028

Tyrosinase-IN-48	Tyrosinase	Neurological Disease Inflammation/Immunology
Tyrosinase-IN-48 (Compound 3) is a potent and competitive chalcone-based tyrosinase inhibitor with an IC₅₀ of 0.49 μM. Tyrosinase-IN-48 has potent antioxidant potential with significant DPPH and ABTS radical scavenging capacity. Tyrosinase-IN-48 can chelate the binuclear copper ions in the active center of tyrosinase and reduce Cu ²⁺ to Cu ⁺, thereby reducing the catalytic activity of the enzyme. Tyrosinase-IN-48 has low cytotoxicity for HEK293 cells and zebrafish embryo. Tyrosinase-IN-48 shows antibrowning effects to improve food quality and can be used for research of food preservation .

Cat. No.	Product Name	Target	Research Area

HY-P5318

MDYYFEER	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P11646

Brazzein	COX	Metabolic Disease Inflammation/Immunology
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC₅₀ of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC₅₀ = 12.55 μM) . Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation .

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