27 Results for "

ACD

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "ACD" in MCE Product Catalog:

213
213 Cited Publications
製品番号: HY-B0579
CAS 番号: 59865-13-3
別名: Cyclosporine A; Ciclosporin A; CsA
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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1 Cited Publications
製品番号: HY-B0579S
別名: Cyclosporine A-d4; Ciclosporin A-d4; CsA-d4
Cyclosporin A-d4 (Cyclosporine A-d4) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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製品番号: HY-B0579R
CAS 番号: 59865-13-3
別名: Cyclosporine A (Standard); Ciclosporin A (Standard); CsA (Standard)
Cyclosporin A (Standard) (Cyclosporine A (Standard)) is the analytical standard of Cyclosporin A (HY-B0579). This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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製品番号: HY-W046325
CAS 番号: 9013-34-7
別名: Diethylaminoethyl cellulose
DEAE-Cellulose (Diethylaminoethyl cellulose) is a positively charged weakly basic cellulose anion exchanger. DEAE-Cellulose exhibits gold recovery activity as well as heparin binding/release activity. DEAE-Cellulose can also be used for the purification of proteins, enzymes and nucleic acids .
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製品番号: HY-P991570
CAS 番号: 2378046-35-4
別名: AD5-10; oba-01 Antibody

研究分野:  

Cancer

Zaptuzumab (AD5-10) is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death (ACD). Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models .
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製品番号: HY-P990676

Target:  

Fc Receptor (FcR)

研究分野:  

Inflammation/Immunology

VIB-9600 is a humanized antibody expressed in CHO cells, targeting FcgR2a/CD32a. VIB-9600 has a huIgG1 type heavy chain and huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for VIB-9600 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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製品番号: HY-10063
CAS 番号: 252870-53-4
純度:  98.24%
別名: TC-1734; ACD3480
Target:  

nAChR

研究分野:  

Neurological Disease

Ispronicline (TC-1734), an orally active, brain-selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist, has shown memory-enhancing properties in rodents and a good tolerability profile. Ispronicline binds to the α4β2 nAChR with high affinity (Ki=11 nM) and is highly selective to other nAChRs such as α7 nAChR and α3β4 nAChR .
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製品番号: HY-P990258
Anti-Mouse CLEC9A/CD370 Antibody (7H11) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CLEC9A/CD370. Anti-Mouse CLEC9A/CD370 Antibody (7H11) reacts with mouse CLEC9A (C-type lectin domain family member 9A) and blocks CLEC9A. Anti-Mouse CLEC9A/CD370 Antibody (7H11) can be used for the researches of cancer and immunology, such as B16.F10-OVA tumor .
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製品番号: HY-W101384
CAS 番号: 37440-01-0
別名: N-Acetyl-D-2-naphthylalanine
研究分野:  

Others

Ac-D-2-Nal-OH (N-Acetyl-D-2-naphthylalanine) can be used as a biochemical assay reagent.
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製品番号: HY-B0579S3
別名: Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4; CsA-13C2,d4
Cyclosporin A- 13C2,d4 (Cyclosporine A- 13C2,d4) is the deuterated, 13C-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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製品番号: HY-114680
CAS 番号: 16231-76-8
Target:  

Insecticide

研究分野:  

Others

ACD-10284 is an insecticide .
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製品番号: HY-P990956
CAS 番号: 2852680-28-3

Target:  

阻害性抗体

研究分野:  

Inflammation/Immunology

HY-P990956 is an CD8A/CD8B-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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製品番号: HY-B0579S2
別名: Cyclosporine A acetate-d4; Ciclosporin A acetate-d4; CsA acetate-d4
Cyclosporin A acetate-d4 (Cyclosporine A acetate-d4) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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製品番号: HY-B0579S5
別名: Cyclosporine A-d12; Ciclosporin A-d12; CsA-d12
Cyclosporin A-d12 (Cyclosporine A-d12) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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製品番号: HY-W044285
CAS 番号: 324017-22-3
研究分野:  

Others

Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .
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製品番号: HY-RS00148
研究分野:  

Others

ACD Human Pre-designed siRNA Set A contains three designed siRNAs for ACD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS17284
研究分野:  

Others

Acd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS23739
研究分野:  

Others

Acd Rat Pre-designed siRNA Set A contains three designed siRNAs for Acd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-124133
CAS 番号: 1238689-36-5
研究分野:  

Cardiovascular Disease

JNJ-42905343 is an orally active and highly selective prolyl hydroxylase (PHD1/2/3) inhibitor with pKI values of 8.07, 7.48 and 7.27 for PHD1, PHD2 and PHD3, respectively. JNJ-42905343 is promising for research of functional iron deficiency (FID) and anemia of chronic disease (ACD) .
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製品番号: HY-B0579S1
CAS 番号: 222295-76-3
別名: Cyclosporine A-d3; Ciclosporin A-d3; CsA-d3
Cyclosporin A-d3 (Cyclosporine A-d3) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion .
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