1 Result for "

ACE2-spike binding

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ACE2-spike binding" in MCE Product Catalog:

Garcinone B
Garcinone B
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Cat. No.: HY-149373
CAS No.: 76996-28-6
Category:  

Plant Guttiferae Extract Phenols Polyphenols Garcinia mangostana Linn. Extract

Target:  

Angiotensin-converting Enzyme (ACE) SARS-CoV NF-κB COX Bacterial IKK

Garcinone B is an NF-κB inhibitor. Garcinone B inhibits LPS-induced NF-κB-dependent transcriptional activation, NF-κB expression, NF-κB-mediated transcription, and IKK, prevents COX-2 transcription, and contributes to immune regulation. Garcinone B inhibits COX enzymes, inhibits prostaglandin E2 release, and contributes to anti-inflammation. Garcinone B blocks ACE2-spike binding, prevents viral entry, inhibits M pro, and prevents polyprotein cleavage and replication. Garcinone B has antibacterial activity against cariogenic bacteria and bactericidal activity against S. mutans. Garcinone B can be used for research on COVID-19, tuberculosis, and dental caries .
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