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3 Results for "
AFP-07
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "AFP-07" in MCE Product Catalog:
Cat. No.: HY-105315
CAS No.: 171232-82-9
Target:
Research Areas:
AFP-07 is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM .
Cat. No.: HY-129293
CAS No.: 788799-13-3
Target:
Research Areas:
AFP-07 free acid is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM .
Cat. No.: HY-129922
CAS No.: 773825-80-2
Target:
Research Areas:
Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki=0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP1-3 and > 10 nM for EP4. 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated.
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