5 Results for "

ALK modulator

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "ALK modulator" in MCE Product Catalog:

Cat. No.: HY-123689
CAS No.: 852626-89-2
Purity:  99.04%
Synonyms: ALKS-33; RDC-0313
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo. Samidorphan can improve the behavior of depressed animals .
loading...
    loading...
Cat. No.: HY-156432
CAS No.: 2447607-85-2
Purity:  99.87%
Research Areas:  

Cancer

ALK-IN-26 is an ALK inhibitor with IC50 value of 7.0 μM for ALK tyrosine kinase. ALK-IN-26 has good pharmacokinetic properties and blood-brain barrier (BBB) permeability. ALK-IN-26 can induce apoptosis, autophagy and necrosis. ALK-IN-26 can be used in glioblastoma studies .
loading...
    loading...
Cat. No.: HY-123689S1
Synonyms: ALKS-33-d5; RDC-0313-d5
Samidorphan-d5 (ALKS-33-d5) is is a deuterated compound of Samidorphan. Samidorphan is an orally active opioid system modulator that binds with high affinity to μ-opioid, κ-opioid, and δ-opioid receptors. Samidorphan is a μ-opioid receptor antagonist and a partial agonist at k-opioid and δ-opioid receptors. Samidorphan acts primarily as an opioid receptor antagonist in vivo .
loading...
    loading...
Cat. No.: HY-123689S
Synonyms: ALKS-33-d4; RDC-0313-d4
Samidorphan-d4 is the deuterium labeled Samidorphan(HY-123689).Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo .
loading...
    loading...
Cat. No.: HY-123689R
CAS No.: 852626-89-2
Synonyms: ALKS-33 (Standard); RDC-0313 (Standard)
Research Areas:  

Neurological Disease

Samidorphan (Standard) is the analytical standard of Samidorphan. This product is intended for research and analytical applications. Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo. Samidorphan can improve the behavior of depressed animals.
loading...
    loading...