2 Results for "

AM1638

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AM1638" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-13467
CAS No.: 1142214-62-7
Purity:  99.65%
Research Areas:  

Metabolic Disease

AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM). AM-1638 increases the expression of antioxidant molecules (HO-1 and NQO-1). AM1638 blocks Palmitate (HY-N0830)-mediated superoxide production and ER stress. AM-1638 has antidiabetic activity and improves glycemic control in BDF mice with diet-induced obesity (DIO). AM-1638 demonstrates excellent oral bioavailability (mouse, >100%; rat, 72%; and cyno, 71%) .
loading...
    loading...
Cat. No.: HY-13467A
CAS No.: 1142222-18-1
(R)-AM-1638 is a R-isomer of AM-1638 (HY-13467). AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM) .
loading...
    loading...