1 Result for "

AP22408

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AP22408" in MCE Product Catalog:

Cat. No.: HY-125064
CAS No.: 268741-43-1
Target:  

Src

Research Areas:  

Cancer

AP22408 is a nonpeptide inhibitor against Src SH2 with an IC50 value of 0.3 μM. AP22408 inhibits rabbit osteoclast-mediated resorption of dentine, exhibits bone-targeting properties based on a hydroxyapatite adsorption assay and demonstrates in vivo antiresorptive activity in a parathyroid hormone-induced rat model. AP22408 is proming for rasearch of osteoporosis and other bone-related diseases such as Paget’s disease, osteolytic bone metastasis and hypercalcemia associated with malignancy .
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