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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
ARM domain
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "ARM domain" in MCE Product Catalog:
Cat. No.: HY-P991092
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Cat. No.: HY-182500A
CAS No.: 3020765-70-9
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(S,S)-SARM1-IN-9 (Compound MY-13A) is a stereoselective SARM1 inhibitor with covalent binding properties. (S,S)-SARM1-IN-9 covalently modifies Cys311 in the autoregulatory ARM domain of wild-type SARM1, thereby blocking NADase activity, without inhibiting the SARM1 C311A or SARM1 C311S mutants. (S,S)-SARM1-IN-9 blocks vacor- and vincristine-induced axon degeneration in primary rodent dorsal root ganglion neurons. (S,S)-SARM1-IN-9 can be used for research on axon degeneration-dependent neurological disorders, including chemotherapy-induced peripheral neuropathy .
Cat. No.: HY-P991092A
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Cat. No.: HY-185782
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Methyltetrazine-PEG2-tris (PEG3-DBCO) is a methyltetrazine-derived multi-arm PEG crosslinker designed specifically for the inverse electron-demand Diels-Alder (IEDDA) bioorthogonal reaction. Methyltetrazine-PEG2-tris (PEG3-DBCO) contains both methyltetrazine and tris (PEG3-DBCO) domains, and carries DBCO reactive groups. Methyltetrazine-PEG2-tris (PEG3-DBCO) serves as a highly efficient bioorthogonal conjugation reagent .
Cat. No.: HY-182500
CAS No.: 3020765-69-6
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SARM1-IN-9 (Compound MY-13B) is a stereoselective SARM1 inhibitor. SARM1-IN-9 is applicable to research related to axon degeneration-dependent neurological diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
