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Cat. No.: HY-185782

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Methyltetrazine-PEG2-tris(PEG3-DBCO)

Methyltetrazine-PEG2-tris (PEG3-DBCO) is a methyltetrazine-derived multi-arm PEG crosslinker designed specifically for the inverse electron-demand Diels-Alder (IEDDA) bioorthogonal reaction. Methyltetrazine-PEG2-tris (PEG3-DBCO) contains both methyltetrazine and tris (PEG3-DBCO) domains, and carries DBCO reactive groups. Methyltetrazine-PEG2-tris (PEG3-DBCO) serves as a highly efficient bioorthogonal conjugation reagent.

For research use only. We do not sell to patients.

Formula: C₁₁₂H₁₄₁N₁₅O₂₅
Molecular Weight:2097.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Methyltetrazine-PEG2-tris(PEG3-DBCO) Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Chemical Information

Molecular Weight 2097.40
Formula C₁₁₂H₁₄₁N₁₅O₂₅
SMILES

O=C(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)NCCOCCOCCC(NC(COCCC(NCCOCCOCCOCCNC(CCC(N3C4C(C#CC5=C(C3)C=CC=C5)C=CC=C4)=O)=O)=O)(COCCC(NCCOCCOCCOCCNC(CCC(N6C7C(C#CC8=C(C6)C=CC=C8)C=CC=C7)=O)=O)=O)COCCC(NCCOCCOCCOCCNC(CCC(N9C%10=C(C#CC%11=C(C9)C=CC=C%11)C=CC=C%10)=O)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xu J, et al. A nitroreductase responsive and photoactivated fluorescent probe for dual-controlled tumor hypoxia imaging. RSC advances. 2022 Aug 22;12(37):23796-23800. [Content Brief]

[2]. Cao W, et al. Reversible control of tetrazine bioorthogonal reactivity by naphthotube-mediated host-guest recognition[J]. Chem, 2023, 9(10): 2881-2901.

[3]. Torres-García D, et al. Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities . RSC chemical biology. 2022 Nov 02;3(11):1325-1330. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Methyltetrazine-PEG2-tris(PEG3-DBCO)

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Methyltetrazine-PEG2-tris(PEG3-DBCO)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Methyltetrazine-PEG2-tris(PEG3-DBCO) Related Classifications

HY-185782 Related Classifications

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