60 Results for "

ARMS

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "ARMS" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99507
CAS No.: 1969309-56-5
Synonyms: MCLA-128; PB4188; R040517

Target:  

EGFR

Domaines de recherche:  

Cancer

Zenocutuzumab (MCLA-128) is a bispecific humanized IgG1 antibody containing two different Fab arms, targeting extracellular domains of HER2 and HER3 .
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Cat. No.: HY-W1048605
8-Arm PEG5000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG5000-Mal can be used for drug delivery .
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Cat. No.: HY-W1048849B
Synonyms: 4-Arm PEG-thiol (MW 10000)
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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Cat. No.: HY-W1048849A
Synonyms: 4-Arm PEG5000-thiol
4-Arm PEG5000-SH (4-Arm PEG5000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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Cat. No.: HY-W1048525
Synonyms: 8-Arm PEG5000-Amine
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-W1048843A
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG5000-amine
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-W1048849C
Synonyms: 4-Arm PEG20000-thiol
4-Arm PEG20000-SH (4-Arm PEG20000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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Cat. No.: HY-W1048843B
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG10000-amine
4-Arm PEG10000-NH2 (4-Arm PEG10000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-W1048527
Synonyms: 8-Arm PEG5000-Thiol
8-Arm PEG5000-SH (8-Arm PEG5000-Thiol) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG5000-SH can be used for drug delivery .
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Cat. No.: HY-W1048519A
Synonyms: 4-Arm PEG10000-amine HCL salt
4-Arm PEG10000-NH2 (4-Arm PEG100000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-102086
CAS No.: 261717-23-1
Domaines de recherche:  

Neurological Disease

MSX3 is an orally active, selective A2a adenosine receptor antagonist and a prodrug of MSX2 (HY-117184). MSX3 reduces hyperphosphorylation of Tau at specific epitopes in mice without altering total Tau levels, Tau fragments, or Tau aggregation in these animals. MSX3 enhances spatial memory. MSX3 regulates effort-related decision-making behaviors. MSX3 reverses D2 antagonist-induced suppression of lever pressing, increased Chow feed intake, reduced selection of high-barrier arms, and prolonged response latency, and also slightly attenuates effects induced by D1 antagonists. MSX3 can be used in the research of Tauopathies (Alzheimer's disease-related), depression, and Parkinsonism .
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Cat. No.: HY-W1048605B
8-Arm PEG10000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG10000-Mal can be used for drug delivery .
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Cat. No.: HY-W1048861D
Synonyms: 4-Arm PEG40000-N3
4-Arm PEG40000-Azide (4-Arm PEG40000-N3) is a multi-arm PEG derivative with an azide group at each end of four arms attached to a pentaerythritol core .
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Cat. No.: HY-W1048527A
Synonyms: 8-Arm PEG20000-Thiol
8-Arm PEG20000-SH (8-Arm PEG20000-Thiol) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG20000-SH can be used for drug delivery .
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Cat. No.: HY-W1048527C
Synonyms: 8-Arm PEG10000-Thiol
8-Arm PEG10000-SH (8-Arm PEG10000-Thiol) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG10000-SH can be used for drug delivery .
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Cat. No.: HY-W1048849D
Synonyms: 4-Arm PEG40000-thiol
4-Arm PEG40000-SH (4-Arm PEG40000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
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Cat. No.: HY-158861
CAS No.: 2933215-86-0
Pureté:  98.5%
Synonyms: G1-nPr-C14E
Target:  

Liposome

Domaines de recherche:  

Others

C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
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Cat. No.: HY-P991016
CAS No.: 2928515-21-1
Synonyms: PT-217

Target:  

CD47

Domaines de recherche:  

Inflammation/Immunology

Peluntamig (PT-217) is a bispecific antibody targeting DLL3 and CD47. The antibody arms of Peluntamig specifically bind to DLL3 on small cell lung cancer tumor cells while blocking the CD47-SIRPa interaction, thereby effectively stimulating macrophage phagocytosis and inducing NK cell-mediated cytotoxicity. Peluntamig exhibits significant anti-tumor activity against small cell lung cancer and also has favorable safety profiles. Peluntamig can be used in a variety of tumor-related studies including those on small cell lung cancer and L1210 leukemia .
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Cat. No.: HY-153718
CAS No.: 2416873-72-6
Domaines de recherche:  

Cancer

KI-ARv-03 is a potent and selective ATP-competitive CDK9 inhibitor with an IC₅₀ of 0.15 μM (at 45 μM ATP), exhibiting over 130-fold selectivity against other CDKs (including CDK1-7). KI-ARv-03 reduces androgen receptor (AR)-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 can be used for leukemia, pancreatic cancer, alveolar rhabdomyosarcoma (ARMS) and castration-resistant prostate cancer (CRPC) research. KI-ARv-03 is a ligand for target protein for PROTAC. KI-ARv-03 can be used to synthesize PROTAC KI-CDK9d-32 (HY-173523) [1][2].
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Cat. No.: HY-W1048843AGL
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG5000-amine (GMP Like)
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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