1 Result for "

Ac-6-FP

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ac-6-FP" in MCE Product Catalog:

Cat. No.: HY-124004
CAS No.: 29769-49-1
Purity:  ≥95.0%
Synonyms: Ac-6-FP
Research Areas:  

Inflammation/Immunology

Acetyl-6-formylpterin (Ac-6-FP) is a hapten that stabilizes MR1 on antigen-presenting cells, forming an MR1:A6FP complex that fails to activate MAIT cell TCR, thereby acting as a competitive inhibitor of MAIT cell activation. Acetyl-6-formylpterin exacerbates house dust mite-induced airway hyperresponsiveness and elevates circulating IgE levels. Acetyl-6-formylpterin reduces systemic MAIT cell activity and decreases the frequency of IL-17A + and IFNγ + MAIT cells in the spleen. Acetyl-6-formylpterin is useful for the study of allergic asthma .
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