1 Result for "

Agios135

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Agios135" in MCE Product Catalog:

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2 Cited Publications
Cat. No.: HY-12475
CAS No.: 1355326-21-4
Purity:  99.43%
Synonyms: Agios 135
Research Areas:  

Cancer

Mutant IDH1-IN-1 (Agios 135) is a selective mutant IDH1 inhibitor with activity against both IDH1 R132H and IDH1 R132C. Mutant IDH1-IN-1 reduces the level of 2-hydroxyglutarate (2-HG), stabilizes mutant IDH1 protein, and restores blocked monocyte differentiation. Mutant IDH1-IN-1 can be used in tumor-related research .
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