20 Results for "

Allergic,contact,dermatitis

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "Allergic,contact,dermatitis" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-13516
CAS No.: 56293-29-9
Purity:  ≥98.0%
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
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2
2 Cited Publications
Cat. No.: HY-N0508
CAS No.: 85026-55-7
Rosin is a natural resin extracted from coniferous trees such as pine trees. Rosin is a frequent contact allergen which induces allergic contact dermatitis. Rosin can be used as emulsifiers, adhesives, and other chemical applications .
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1
1 Cited Publications
Cat. No.: HY-108170
CAS No.: 121-29-9
Purity:  31.27%
Pyrethrin II is an orally active insecticidal ester of chrysanthemum acid found in Chrysanthemum cinerariifolium and C. coccineum Willd., an active constituent of pyrethrum extract with low mammalian toxicity. Pyrethrin II exhibits antiparasitic activity. Pyrethrin II can be used for the research of allergic contact dermatitis and parasitic infections .
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Cat. No.: HY-Y0912
CAS No.: 94790-37-1
Synonyms: N-HBTU
Research Areas:  

Inflammation/Immunology

HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
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Cat. No.: HY-W041608
CAS No.: 26172-55-4
Methylchloroisothiazolinone is a widely used fungicide and also an aquatic pollutant with pro-inflammatory activity and neurotoxicity. Methylchloroisothiazolinone induces the production of pro-inflammatory cytokines (such as IL-1β, TNF-α, IL-6) by activating the NF-κB signaling pathway and upregulating TLR4 expression, thereby triggering allergic contact dermatitis. Methylchloroisothiazolinone reduces cholinesterase activity and exacerbates oxidative stress by impairing catalase activity and disrupting redox balance. Methylchloroisothiazolinone poses significant harm to Mediterranean mussels, reducing the viability of hemocytes and digestive gland cells, inhibiting immune phagocytic function, and disrupting osmoregulatory capacity. Methylchloroisothiazolinone is used in studies on allergic contact dermatitis and related immunotoxicity mechanisms .
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Cat. No.: HY-W014605
CAS No.: 886-38-4
Synonyms: Diphencyprone
Diphenylcyclopropenone (Diphencyprone) is a potent hapten acting as a topical immunomodulatory agent, which induces an allergic contact dermatitis. Diphenylcyclopropenone induces an increase of cell-surface thiols in cells of a human monocytic cell line, THP-1. Diphenylcyclopropenone acts on the autoreactive T-lymphocytes within the follicular milieu to induce Apoptosis. Diphenylcyclopropenone can be used for alopecia areata research .
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Cat. No.: HY-W020246
CAS No.: 97-74-5
Synonyms: TMTM
Tetramethylthiuram monosulfide (TMTM) is an orally active microsomal monooxygenases inhibitor. Tetramethylthiuram monosulfide is used as an accelerator and activator in the processing of natural rubber and butyl rubber. Tetramethylthiuram monosulfide reduces palmitic acid incorporation into microsomal phospholipids, disrupts microsomal membrane integrity, and impairs electron transport during oxygenation. Tetramethylthiuram monosulfide can be used for the research of fungal infection, bacterial infection and allergic contact dermatitis .
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Cat. No.: HY-B1419
CAS No.: 90-01-7
Synonyms: 2-Hydroxybenzyl alcohol; Saligenin
Salicyl alcohol (2-Hydroxybenzyl alcohol; Saligenin) is a phenolic alcohol-type topical anesthetic and strong sensitizer with antiseptic, antibacterial and antipyretic activities. Salicyl alcohol serves as a precursor for salicin synthesis. Salicyl alcohol induces contact dermatitis and eczematous skin reactions, and is a well-known allergen identified in phenolic resins. Salicyl alcohol is isolated from the barks of European aspen (Populus tremula), rowan (Sorbus aucuparia) and willow (Salix spp.). Salicyl alcohol is used in studies related to allergic contact dermatitis .
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Cat. No.: HY-W099729
CAS No.: 70445-33-9
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Ethylhexylglycerin is an antibacterial agent. Ethylhexylglycerin can induce allergic contact dermatitis. Ethylhexylglycerin inhibits the growth of various bacteria, disrupts the integrity of bacterial cell membranes, and causes proton leakage, reduced ATP levels, morphological abnormalities, and DNA aggregation. Ethylhexylglycerin serves as a skin conditioning agent, deodorant active ingredient, and preservative synergist. Ethylhexylglycerin is applicable to research related to contact dermatitis and bacterial infections .
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Cat. No.: HY-P10940
CAS No.: 845727-63-1
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Ac-RFAAKAA-COOH is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH forms stable covalent adducts with isothiocyanates, resulting in peptide depletion over time. Ac-RFAAKAA-COOH acts as a model peptide in direct peptide reactivity assays, where its chemical reactivity is evaluated via fluorescamine-based free amine assays. Ac-RFAAKAA-COOH can be used in studies related to allergic contact dermatitis and skin sensitization .
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Cat. No.: HY-N0508R
CAS No.: 85026-55-7
Rosin (Standard) is the analytical standard of Rosin. This product is intended for research and analytical applications. Rosin is a natural resin extracted from coniferous trees such as pine trees. Rosin is a frequent contact allergen which induces allergic contact dermatitis. Rosin can be used as emulsifiers, adhesives, and other chemical applications .
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Cat. No.: HY-186038
CAS No.: 10264-38-7
Research Areas:  

Inflammation/Immunology

Cyanoethyl dimethyldithiocarbamate, a dithiocarbamate-related substance, is a contact allergen. Cyanoethyl dimethyldithiocarbamate can be found in accelerator-free and conventional nitrile gloves. Cyanoethyl dimethyldithiocarbamate can be used for the research of allergic contact dermatitis .
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Cat. No.: HY-13516R
CAS No.: 56293-29-9
Aloperine (Standard) is the analytical standard of Aloperine. This product is intended for research and analytical applications. Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
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Cat. No.: HY-W040536
CAS No.: 6440-58-0
Synonyms: Dimethyloldimethyl hydantoin
Research Areas:  

Infection

DMDM hydantoin (Glydant) is an allergen and formaldehyde-releasing preservative. DMDM hydantoin releases formaldehyde under regulation by multiple factors and with enhanced release in alkaline environments. DMDM hydantoin induces allergic contact dermatitis via type-IV delayed hypersensitivity, either directly or through released formaldehyde. DMDM hydantoin is a broad-spectrum preservative that is effective against fungi, yeast, and gram-positive and gram-negative bacteria. DMDM hydantoin can be used in cosmetics industry production research (e.g., shampoos, hairsprays, and skincare products) and can be used for research on allergic contact dermatitis .
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Cat. No.: HY-119958
CAS No.: 74161-27-6
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

Acamelin is a Benzofuranoquinone compound that acts as a contact sensitizer. It can be isolated from the heartwood of Acacia melanoxylon R. Br., an Australian blackwood. Acamelin induces positive skin reactions and contact allergy in guinea pigs. It is applicable to research related to allergic contact dermatitis .
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Cat. No.: HY-187232
CAS No.: 2536-05-2
Synonyms: 2,2′-MDI
Target:  

Drug Isomer

Research Areas:  

Inflammation/Immunology

2,2'-Methylenediphenyl diisocyanate (2,2′-MDI) is a sensitizer and an isomer of methylenediphenyl diisocyanate (MDI). 2,2'-Methylenediphenyl diisocyanate induces contact sensitization upon skin contact. 2,2'-Methylenediphenyl diisocyanate is used in studies of allergic contact dermatitis .
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Cat. No.: HY-D0573
CAS No.: 52372-39-1
Synonyms: Solvent red 197; Fluorescent Red GK
C.I. Solvent Red 197 (Solvent Red 197; Fluorescent Red GK) is a high-temperature-resistant fluorescent bluish-red dye that is widely used for coloring polymers, plastics, fibers, printing inks, and hydrocarbon products (such as lubricants and candles). C.I. Solvent Red 197 does not induce allergic contact dermatitis .
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Cat. No.: HY-N18979A
CAS No.: 117405-49-9
trans-p-Coumaric acid 4-O-β-D-glucopyranoside is an orally active phenolic glycoside and hydroxycinnamic acid derivative with high plasma exposure following oral administration in mice. trans-p-Coumaric acid 4-O-β-D-glucopyranoside can be used in studies related to allergic contact dermatitis .
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Cat. No.: HY-187152
CAS No.: 83258-37-1
Target:  

Fungal Bacterial

Urushiol (15:2) is a 3-substituted catechol with a 15-carbon side chain containing 2 double bonds, and it exists in the sap, bark and lacquer fluid of Rhus vernicifera and Toxicodendron vernicifluum. Urushiol (15:2) is used for research on cancer, fungal infections, bacterial infections and allergic contact dermatitis .
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Cat. No.: HY-NP229
DNP-BSA is a multivalent antigen and protein-binding reagent. DNP-BSA binds to subdomain IIA (Site I) of bovine serum albumin via predominantly hydrophobic forces, with spontaneous complex formation via combined dynamic and static quenching. DNP-BSA induces cross-linking of IgE-bound FceRI, triggering tyrosine phosphorylation of FceRI β and γ subunits. DNP-BSA binds to anti-DNP IgE via its DNP groups, forming cross-links between IgE-FceRI complexes, with most DNP groups initially unavailable but transiently exposed for binding. DNP-BSA induces FITC fluorescence quenching in FITC-labeled anti-DNP IgE, proportional to occupied IgE Fab binding sites. DNP-BSA can be used for the research of allergy, inflammation, and contact sensitivity (allergic contact dermatitis) .
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