3 Results for "

Almotriptan malate

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Almotriptan malate" in MCE Product Catalog:

Cat. No.: HY-B0383
CAS No.: 181183-52-8
Synonyms: PNU180638
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Almotriptan malate (PNU180638) is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan malate shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan malate induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan malate can be used in research related to migraine .
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Cat. No.: HY-B0383R
CAS No.: 181183-52-8
Synonyms: PNU180638 (Standard)
Research Areas:  

Neurological Disease

Almotriptan (malate) (Standard) is the analytical standard of Almotriptan (malate). This product is intended for research and analytical applications.
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Cat. No.: HY-143797S
Almotriptan-d6 (PNU180638-d6) maleate is the deuterium labeled Almotriptan maleate. Almotriptan malate is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan malate shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan malate induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan malate can be used in research related to migraine.
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