Almotriptan malate (Standard)
Almotriptan malate (Standard) is the analytical standard of Almotriptan malate (HY-B0383). This product is intended for research and analytical applications. Almotriptan malate (PNU180638) is an orally active, highly selective agonist of the 5-HT1B/1D receptor (5-HT1B/1D receptor), with EC50 values of 1.6 nM and 3.1 nM, respectively. Almotriptan malate shows moderate affinity for the 5-HT1F receptor, and weak affinity for the 5-HT1A, 5-HT6 and 5-HT7 receptors. Almotriptan malate induces intracranial vasoconstriction, inhibits nociceptive neurotransmission in the trigeminocervical complex, and suppresses the release of vasoactive peptides from trigeminal nerve endings. Almotriptan malate can be used in research related to migraine.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98%
- CAS. Nr.: 181183-52-8
- Formel: C21H31N3O7S
- Molecular Weight:469.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-B0383
Almotriptan malate -
HY-B0121
Sumatriptan succinate -
HY-B0206
Rizatriptan benzoate -
HY-B0197A
Naratriptan hydrochloride -
HY-B1180
Vinburnine -
HY-B1658A
Frovatriptan succinate hydrate -
HY-B0121R
Sumatriptan succinate (Standard) -
HY-B0206R
Rizatriptan benzoate (Standard) -
HY-B0197AR
Naratriptan hydrochloride (Standard) -
HY-B1658AR
Frovatriptan succinate hydrate (Standard) -
HY-B1180R
Vinburnine (Standard)
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 181183-52-8
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Molecular Weight 469.55
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Formel C21H31N3O7S
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SMILES
O=C(O)C(O)CC(O)=O.O=S(CC1=CC2=C(NC=C2CCN(C)C)C=C1)(N3CCCC3)=O
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Synonyms
PNU180638 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Bou J , et al. Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine. Eur J Pharmacol, 2000. 410(1): p. 33-41. [Content Brief]
[2]. Gras J, et al. Safety profile of almotriptan, a new antimigraine agent. Effects on central nervous system, renal function and respiratory dynamics. Arzneimittelforschung, 2001. 51(9): p. 726-32. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Almotriptan malate (Standard) Related Classifications
HY-B0383R Related Classifications
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