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Results for "

Antiparasitic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (7) Adenosine Kinase (1) Adrenergic Receptor (3) Akt (1) Aminoacyl-tRNA Synthetase (1) Aminopeptidase (1) AMPK (1) Angiotensin Receptor (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (28) Apoptosis (23) Autophagy (10) Bacterial (38) Bcl-2 Family (2) BCRP (4) Biochemical Assay Reagents (1) Calcium Channel (1) Carbonic Anhydrase (1) Caspase (3) Cathepsin (2) Chloride Channel (3) Cholinesterase (ChE) (2) Clathrin (1) CRFR (3) Dihydrofolate reductase (DHFR) (4) DNA/RNA Synthesis (3) Drug Derivative (2) Drug Intermediate (2) Drug Isomer (4) Drug Metabolite (5) Endogenous Metabolite (10) Environmental Pollutants (4) ERK (3) Farnesyl Transferase (3) Fluorescent Dye (1) Fructose-1,6-bisphosphate aldolase (1) Fungal (21) GABA Receptor (3) Glutathione S-transferase (1) HDAC (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (3) HSV (2) Influenza Virus (1) Insecticide (2) Interleukin Related (4) Isotope-Labeled Compounds (18) JAK (2) Lactate Dehydrogenase (1) mAChR (5) Methylenetetrahydrofolate Dehydrogenase (MTHFD) (1) Microtubule/Tubulin (4) Mitochondrial Metabolism (3) MMP (1) mRNA (1) mTOR (3) Na+/K+ ATPase (1) nAChR (7) Necroptosis (2) NF-κB (7) Oxidative Phosphorylation (2) P-glycoprotein (2) p38 MAPK (4) Parasite (250) PARP (2) Phosphatase (5) Phosphodiesterase (PDE) (1) Phospholipase (1) PI3K (3) PI4K (1) Platelet-activating Factor Receptor (PAFR) (1) Proteasome (3) Raf (2) Reactive Oxygen Species (ROS) (11) Reference Standards (38) Reverse Transcriptase (3) SARS-CoV (6) Sirtuin (3) STAT (3) TNF Receptor (3) Topoisomerase (3) TRP Channel (1) VD/VDR (1) α-synuclein (2) γ-Glutamyl Transferase (GGT) (2)
By Research Areas:	Cancer (58) Cardiovascular Disease (10) Infection (258) Inflammation/Immunology (44) Metabolic Disease (14) Neurological Disease (34)
Oligonucleotides:	mRNA (1) Interleukin & Receptors (1)

280

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-B0879A

Suramin sodium salt 20+ Cited Publications Suramin hexasodium salt	Phosphatase Sirtuin Reverse Transcriptase Topoisomerase SARS-CoV Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor . Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC₅₀=297 nM), SirT2 (IC₅₀=1.15 μM), and SirT5 (IC₅₀=22 μM) . Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC₅₀=5 μM) . Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor . Suramin sodium salt efficiently inhibits IP5K and is an *antiparasitic, anti-neoplastic and anti*-angiogenic agent .

HY-N6735

Apicidin 5 Publications Verification OSI 2040	HDAC Parasite	Infection Cancer
Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-10969

Obatoclax Mesylate 10+ Cited Publications GX15-070 Mesylate	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax Mesylate (GX15-070 Mesylate), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax Mesylate induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax Mesylate has anti-cancer and broad-spectrum *antiparasitic* activity .

HY-B0740

Cyclobenzaprine hydrochloride MK130 hydrochloride	5-HT Receptor Parasite	Infection Neurological Disease
Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT₂ receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases .

HY-B0413

Fenbendazole 5+ Cited Publications	Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection Cancer
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad *antiparasitic* range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-15308

Avermectin B1a 1 Publications Verification Abamectin B1a	Parasite Antibiotic	Infection
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.

HY-N1451

Betulonic acid 5 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Parasite HSV	Infection Inflammation/Immunology Cancer
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Parasite NF-κB p38 MAPK Phosphatase Apoptosis	Infection Cancer
Bruceine A (Dihydrobrusatol) is a natural quassinoid. Bruceine A is an inhibitor of parasites, NF-κB, and PFKFB4 (K_d: 44 nM). Bruceine A is an activator of P38α MAPK. Bruceine A has antiparasitic activity. Bruceine A has antitumor activity and inhibits cancer cell migration. Bruceine A blocks the cell cycle and induces apoptosis. Bruceine A can be used in parasites, pancreatic cancer, and breast cancer research .

HY-122975

Metronidazole Benzoate Benzoyl metronidazole	Bacterial Parasite	Infection
Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .

HY-12724

Guanabenz 2 Publications Verification	Adrenergic Receptor Parasite	Cardiovascular Disease Cancer
Guanabenz is an orally active α-2-adrenoceptor agonist. Guanabenz has antihypertensive effect and antiparasitic activity. Guanabenz interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz also is used for the research of high blood pressure .

HY-B0879

Suramin	Phosphatase Sirtuin Reverse Transcriptase Topoisomerase SARS-CoV Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Suramin is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor . Suramin is a potent inhibitor of sirtuins: SirT1 (IC₅₀=297 nM), SirT2 (IC₅₀=1.15 μM), and SirT5 (IC₅₀=22 μM) . Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC₅₀=5 μM) . Suramin is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor .Suramin efficiently inhibits IP5K and is an *antiparasitic, anti-neoplastic and anti*-angiogenic agent .

HY-B1400

Diiodohydroxyquinoline 2 Publications Verification Iodoquinol; 5,7-Diiodo-8-hydroxyquinoline; 5,7-Diiodo-8-quinolinol	Environmental Pollutants Parasite SARS-CoV	Infection Inflammation/Immunology
Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC₅₀ value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .

HY-17598

Rafoxanide 5+ Cited Publications	Oxidative Phosphorylation Parasite p38 MAPK Raf Apoptosis	Infection Cancer
Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research .

HY-B0937A

Amprolium hydrochloride	Parasite	Infection
Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption .

HY-12724A

Guanabenz hydrochloride	Parasite Adrenergic Receptor	Cardiovascular Disease Cancer
Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist. Guanabenz hydrochloride has antihypertensive effect and antiparasitic activity. Guanabenz hydrochloride interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz hydrochloride also is used for the research of high blood pressure .

HY-B0413S

Fenbendazole-d3 5 Publications Verification	HIF/HIF Prolyl-Hydroxylase Parasite Microtubule/Tubulin Antibiotic	Infection
Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-N7141

Spiramycin I 1 Publications Verification	Antibiotic Parasite Bacterial	Infection
Spiramycin I is a macrolide antibiotic and *antiparasitic* .

HY-10969A

Obatoclax 10+ Cited Publications GX15-070	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum *antiparasitic* activity .

HY-B0945

Nitromide 1 Publications Verification 3,5-Dinitrobenzamide	Parasite	Infection
Nitromide is an anti-parasitic agent.

HY-N7227

Anonaine	Glutathione S-transferase Parasite	Infection Cancer
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-B0263S

Thiabendazole-d4 2-(4-Thiazolyl)benzimidazole-d₄	Mitochondrial Metabolism Parasite	Others
Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent .

HY-N10220

Paraherquamide E	Endogenous Metabolite Parasite	Infection
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-120809

Spiramycin III	Bacterial Parasite Antibiotic	Infection
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-B0413R

Fenbendazole (Standard)	Reference Standards Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection
Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad *antiparasitic* range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-125729

Ivermectin B1b	Parasite SARS-CoV	Infection
Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .

HY-146045

Antiparasitic agent-7	Parasite	Infection
Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC₅₀ = 10.61 μM) .

HY-179690

Antiparasitic agent-30	Parasite Adenosine Kinase	Infection
Antiparasitic agent-30 is a potent adenosine kinase TbrAK modulator and antitrypanosomal agent. Antiparasitic agent-30 exhibits significant inhibitory activity against Trypanosoma brucei rhodesiense, while enhancing the activity of recombinant TbrAK(EC₅₀=38 nM, K_a=75 nM-497 nM). Antiparasitic agent-30 exerts its pharmacological effects by eliminating intrinsic substrate inhibition and hyperactivating TbrAK in Trypanosoma brucei rhodesiense. Antiparasitic agent-30 serves as a valuable tool molecule for studying acute African human trypanosomiasis (sleeping sickness) .

HY-W106742

Propoxybenzene Propyl phenyl ether	Drug Intermediate Parasite	Infection
Propoxybenzene (Propyl phenyl ether) is a dialkoxybenzene intermediate. Propoxybenzene has *antiparasitic* activity. Propoxybenzene can be used in the study of Varroa mite infestation .

HY-161666

mCMY416	Aminoacyl-tRNA Synthetase Parasite	Infection
mCMY416 is an orally active and blood brain barrier (BBB) permeability apicomplexan phenylalanine tRNA synthetase inhibitor, and shows antiparasitic activity .

HY-W783297

8a-OH-Avermectin B1a	Parasite	Infection
8a-OH-Avermectin B1a is a key primary monooxygenated degradate generated during the photodegradation of Avermectin B1a (HY-15308). 8a-OH-Avermectin B1a can be used for the study of antiparasitic infection .

HY-P3917

Lactoferricin B (4-14), bovine LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-NP0222

Apolactoferrin	Parasite	Infection
Apolactoferrin is an iron-free form of lactoferrin with antiparasitic activity. Apolactoferrin is an iron-binding protein .

HY-157314

HDAC6-IN-27	HDAC Parasite	Infection
HDAC6-IN-27 (compound 8C) is a HDAC inhibitor with IC₅₀ vales of 15.9 nM 136.5 nM and 6180.2 nM for HDAC6, HDAC8 and HDAC1, respectively. HDAC6-IN-27 shows potent antiparasitic effects .

HY-N11920

Kadsurenin B	Platelet-activating Factor Receptor (PAFR)	Infection Neurological Disease Inflammation/Immunology
Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc .

HY-129278

Lunarine	Parasite	Infection Cardiovascular Disease Neurological Disease
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD₅₀ of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with K_i of 304 μM .

HY-149078

Antiparasitic agent-14	Parasite	Infection
Antiparasitic agent-14 is a potent *antiparasitic* agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote .

HY-B0226A

(E)-Nitrofurazone (E)-Nitrofural	Bacterial Parasite	Infection
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .

HY-147806

Antiparasitic agent-8	Parasite	Infection
Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity .

HY-B0879AR

Suramin sodium salt (Standard) Suramin hexasodium salt (Standard)	Reference Standards Phosphatase Sirtuin Reverse Transcriptase Topoisomerase SARS-CoV Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Suramin (sodium salt) (Standard) is the analytical standard of Suramin (sodium salt). This product is intended for research and analytical applications. Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor . Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC₅₀=297 nM), SirT2 (IC₅₀=1.15 μM), and SirT5 (IC₅₀=22 μM) . Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC₅₀=5 μM) . Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor . Suramin sodium salt efficiently inhibits IP5K and is an *antiparasitic, anti-neoplastic and anti*-angiogenic agent .

HY-B1400R

Diiodohydroxyquinoline (Standard) Iodoquinol (Standard); 5,7-Diiodo-8-hydroxyquinoline (Standard); 5,7-Diiodo-8-quinolinol (Standard)	Reference Standards Parasite SARS-CoV	Infection Inflammation/Immunology
Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .

HY-151133

Antiparasitic agent-9	Parasite	Infection
Antiparasitic agent-9 (compound 47) is an orally active and potent antiparasitic agent. Antiparasitic agent-9 shows antiparasitic activity against the human parasite .

HY-N8483

Eprinomectin B1a	Parasite Drug Metabolite	Infection
Eprinomectin B1a is a Eprinomectin (HY-12643) metabolite (an antiparasitic compound) .

HY-175364

Antiparasitic agent-27	Parasite Reactive Oxygen Species (ROS)	Infection
Antiparasitic agent-27 (Compound 2) is a potent antiparasitic agent targeting Leishmania infantum (IC₅₀=3.1 μM). Antiparasitic agent-27 induces G0/G1 cell cycle arrest and reactive oxygen species (ROS) generation to trigger programmed cell death. Antiparasitic agent-27 is promising for research of visceral leishmaniasis (VL) .

HY-175507

TRPMPZQ-IN-1	Parasite TRP Channel	Infection
TRPMPZQ-IN-1 (Compound 52) is a TRPM_PZQ inhibitor, with an EC₅₀ of 0.38 μM against TRPM_PZQ from Spirometra erinaceieuropaei. TRPMPZQ-IN-1 exhibits antiparasitic activity, showing an EC₅₀ of 4.3 μM against Echinococcus multilocularis. TRPMPZQ-IN-1 can be used in antiparasitic research .

HY-118495

Cardol diene	Parasite	Infection
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-157466

Antiparasitic agent-21	Parasite	Infection
Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC₅₀ of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability .

HY-146043

Antiparasitic agent-5	Parasite	Infection
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC₅₀ = 6.78 μM) .

HY-146044

Antiparasitic agent-6	Parasite	Infection
Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC₅₀ = 13.64 μM) .

HY-149960

Antiparasitic agent-17	Parasite	Infection
Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC₅₀s of 0.96 μM and 1.67 μM, respectively .

HY-146042

Antiparasitic agent-4	Parasite	Infection
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC₅₀s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC₅₀ = 18.97 μM) .

Cat. No.	상품명

HY-L082

Antiparasitic Compound library

644 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 644 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

Cat. No.	상품명	Type

HY-W012550

D-Carnitine	Biochemical Assay Reagents
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity .

HY-NP0222

Apolactoferrin	Biochemical Assay Reagents
Apolactoferrin is an iron-free form of lactoferrin with antiparasitic activity. Apolactoferrin is an iron-binding protein .

HY-W012550R

D-Carnitine (Standard)	Biochemical Assay Reagents
D-Carnitine (Standard) is the analytical standard of D-Carnitine. This product is intended for research and analytical applications. D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity .

Cat. No.	상품명	Target	Research Area

HY-P1975

Aureobasidin A 3 Publications Verification Basifungin	Antibiotic Fungal Parasite	Infection Inflammation/Immunology
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and *antiparasitic* activity .

HY-P1752

Urocortin II, human	CRFR Bacterial Parasite NF-κB ERK	Metabolic Disease
Urocortin II, human is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. Urocortin II, human has an effect of promoting satiet and neuroprotective effect. Urocortin II, human also has bactericidal, *antiparasitic* and pro-inflammation activity. Urocortin II, human can activate NF-κB pathway and ERK1/2 MAP kinase. Urocortin II, human can reduce pulmonary arterial hypertension and shows cardiac protection effect. Urocortin II, human can be used for the researches of infection, inflammation, metabolic, neurological and cardiovascular disease .

HY-P1752B

Urocortin II, human acetate	CRFR Bacterial Parasite NF-κB ERK	Metabolic Disease
Urocortin II, human acetate is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. Urocortin II, human acetate has an effect of promoting satiet and neuroprotective effect. Urocortin II, human acetate also has bactericidal, *antiparasitic* and pro-inflammation activity. Urocortin II, human acetate can activate NF-κB pathway and ERK1/2 MAP kinase. Urocortin II, human acetate can reduce pulmonary arterial hypertension and shows cardiac protection effect. Urocortin II, human acetate can be used for the researches of infection, inflammation, metabolic, neurological and cardiovascular disease .

HY-P3917

Lactoferricin B (4-14), bovine LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P11155

Halictine 2	Parasite	Infection
Halictine 2 is an antimicrobial peptide. Halictine 2 exhibits promising anti-parasitic activity against Leishmania spp., targeting both the extracellular infective metacyclic promastigotes and intracellular amastigotes. Halictine 2 can be used for the study of leishmaniases .

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P1752A

Urocortin II, human TFA	CRFR Bacterial Parasite NF-κB ERK	Metabolic Disease
Urocortin II, human TFA is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor. Urocortin II, human TFA has an effect of promoting satiet and neuroprotective effect. Urocortin II, human TFA also has bactericidal, *antiparasitic* and pro-inflammation activity. Urocortin II, human TFA can activate NF-κB pathway and ERK1/2 MAP kinase. Urocortin II, human TFA can reduce pulmonary arterial hypertension and shows cardiac protection effect. Urocortin II, human TFA can be used for the researches of infection, inflammation, metabolic, neurological and cardiovascular disease .

HY-P2209

Nummularine B Daechuine S27; N-Demethylamphibine H	Parasite Phosphodiesterase (PDE)	Infection
Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC₅₀ of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca ²⁺-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N0176

Dihydroartemisinin Maximum Cited Publications 45 Publications Verification Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Disease Research Fields Source Classification	Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite
Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays *antiparasitic* activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .

HY-N2364

Arecoline 5 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Metabolic Disease Plants Infection Alkaloids Piperidine Alkaloids Palmae Inflammation/Immunology Disease Research Fields Source Classification	mAChR nAChR
Arecoline, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress .

HY-50730

Asparagusic acid 4 Publications Verification	Infection Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Plants Disease Research Fields Source Classification Asparagus officinalis L.	Parasite Endogenous Metabolite
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-P1975

Aureobasidin A 3 Publications Verification Basifungin	Infection Microorganisms Antifungal Classification of Application Fields Antibiotics Disease Research Inflammation/Immunology Disease Research Fields Other Antibiotics Source Classification	Antibiotic Fungal Parasite
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and *antiparasitic* activity .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Parasite Antibiotic
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-B0489

Arecoline hydrobromide 5 Publications Verification methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Metabolic Disease Plants Infection Alkaloids Other Alkaloids Palmae Inflammation/Immunology Disease Research Fields Source Classification	mAChR nAChR
Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-W071746

Linolelaidic acid 1 Publications Verification Linoelaidic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Parasite Apoptosis
Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections .

HY-N6735

Apicidin 5 Publications Verification OSI 2040	Infection Microorganisms Classification of Application Fields Antibiotics Anti-parasitic Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification	HDAC Parasite
Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-N1451

Betulonic acid 5 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Infection Triterpenes other families Classification of Application Fields Terpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Parasite HSV
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Infection Triterpenes Simaroubaceae Classification of Application Fields Terpenoids Plants Disease Research Fields Brucea javanica (L.) Merr. Source Classification	Parasite NF-κB p38 MAPK Phosphatase Apoptosis
Bruceine A (Dihydrobrusatol) is a natural quassinoid. Bruceine A is an inhibitor of parasites, NF-κB, and PFKFB4 (K_d: 44 nM). Bruceine A is an activator of P38α MAPK. Bruceine A has antiparasitic activity. Bruceine A has antitumor activity and inhibits cancer cell migration. Bruceine A blocks the cell cycle and induces apoptosis. Bruceine A can be used in parasites, pancreatic cancer, and breast cancer research .

HY-17035

Doramectin 5 Publications Verification	Infection Microorganisms Antibiotics Anti-parasitic Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Parasite Antibiotic Bacterial
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .

HY-W018025

5,6-Dihydroxyindole	Natural Products Classification of Application Fields Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, *antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-B0778

Milbemycin oxime 1 Publications Verification	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Antibiotic Parasite
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-121054

Chalcone 1 Publications Verification (E/Z)-Benzylideneacetophenone	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Parasite
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-W016586

Acivicin 2 Publications Verification AT-125; U-42126	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite γ-Glutamyl Transferase (GGT)
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-W016586A

Acivicin hydrochloride 2 Publications Verification AT-125 hydrochloride; U-42126 hydrochloride	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-75247

Coumaran 2 Publications Verification 2,3-Dihydrobenzofuran	Natural Products Verbenaceae Plants Endogenous metabolite Lantana camaraLinn. Source Classification	Cholinesterase (ChE) Endogenous Metabolite Parasite
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide. .

HY-N3544

Caryophyllene oxide (-)-Caryophyllene oxide	Structural Classification Hymenaea courbaril L. Classification of Application Fields Leguminosae Terpenoids Sesquiterpenes Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Cancer	Environmental Pollutants Apoptosis Bacterial Fungal Parasite
Caryophyllene oxide ((-)-Caryophyllene oxide) is a bicyclic sesquiterpene with anticancer effects. Caryophyllene oxide induces apoptosis of PC-3 cells. Caryophyllene oxide shows analgesic and anti-inflammatory activities. Caryophyllene oxide has insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties .

HY-N0397

Harpagide	Iridoids Classification of Application Fields Scrophularia ningpoensis Hemsl. Terpenoids Scrophulariaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	Parasite
Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (*T.b. rhodesiense) with an IC₅₀* of 21 μg/mL. Harpagide exerts significant antileishmanial activity against *L. donovani* with an IC₅₀ value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .

HY-N0078

Ginkgolic Acid (C13:0) Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid	Infection Monophenols Ginkgoaceae Classification of Application Fields Ketones, Aldehydes, Acids Phenols Plants Ginkgo biloba Disease Research Fields Source Classification	Bacterial PI3K Parasite
Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC₅₀: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC₅₀: 2.40 μM) .

HY-12538

Graveoline Rutamine	Structural Classification Alkaloids Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants Source Classification	Apoptosis Autophagy Fungal Parasite Reactive Oxygen Species (ROS) Interleukin Related JAK STAT
Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury .

HY-N7141

Spiramycin I 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Disease Research Disease Research Fields Source Classification	Antibiotic Parasite Bacterial
Spiramycin I is a macrolide antibiotic and *antiparasitic* .

HY-N6015

Bacopasaponin C	Triterpenes Classification of Application Fields Terpenoids Scrophulariaceae Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst. Source Classification Cancer	Parasite P-glycoprotein
Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC₅₀ of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani .

HY-N7227

Anonaine	Alkaloids Annona crassiflora Mart. Quinoline Alkaloids Plants Annonaceae Source Classification	Glutathione S-transferase Parasite
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-108170

Pyrethrin II 1 Publications Verification	Structural Classification Natural Products Lycium barbarum L. Classification of Application Fields Other Diseases Solanaceae Plants Disease Research Fields Biological Pesticide Research Source Classification Agricultural Research	Insecticide Parasite
Pyrethrin II is an orally active insecticidal ester of chrysanthemum acid found in Chrysanthemum cinerariifolium and C. coccineum Willd., an active constituent of pyrethrum extract with low mammalian toxicity. Pyrethrin II exhibits *antiparasitic* activity. Pyrethrin II can be used for the research of allergic contact dermatitis and parasitic infections .

HY-N0413

Hupehenine	Alkaloids Liliaceae Classification of Application Fields Fritillaria hupehensis Hsiao et K. C. Hsia Plants Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	α-synuclein Reactive Oxygen Species (ROS) Apoptosis Autophagy Parasite
Hupehenine is an orally active isosteroidal alkaloid that can be extracted from F. hupehensis. Hupehenine exhibits activities such as antitussive, expectorant, anticancer, and antiparasitic. In vitro, Hupehenine can also inhibit α-synuclein seeded fibril formation, making it applicable for the research of Parkinson's disease and other related disorders .

HY-N10220

Paraherquamide E	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Endogenous Metabolite Parasite
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-120809

Spiramycin III	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Bacterial Parasite Antibiotic
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-W718418

3-Ketoadipic acid	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Drug Derivative
3-Ketoadipic acid is a dicarboxylic acid containing a keto group that can be isolated from Brazilian propolis (Et-Bra). Brazilian propolis exhibits antibacterial, antifungal, and antiparasitic activities .

HY-N11173A

trans-Melilotoside	Structural Classification Leguminosae Dendranthema morifolium (Ramat.) Tzvel. Coumarins Phenylpropanoids Plants Source Classification	Parasite
trans-Melilotoside is a coumarin precursor and that can be isolated from Melilotus neapolitan. trans-Melilotoside exhibits *antiparasitic* and DPPH radical-scavenging activity. trans-Melilotoside can be used for the research of human african trypanosomiasis, chagas’ disease, malaria ^[1] ^[3].

HY-N8213

Rapanone	Infection Quinones Classification of Application Fields Benzene Quinones Embelia laeta (Linn.) Mez Plants Myrsinaceae Inflammation/Immunology Disease Research Fields Source Classification	Apoptosis Phospholipase Bacterial Parasite
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA₂ inhibitor, with an IC₅₀ of 2.6 μM .

HY-N0924A

(±)-Stylopine hydrochloride 1 Publications Verification Tetrahydrocoptisine hydrochloride	Alkaloids Classification of Application Fields Flacourtia indica Flacourtiaceae Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Source Classification	Parasite
(±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-118383

Agathisflavone	Flavonoids Flavones Araucariaceae Agathis robusta (C. Moore ex F. Muell.) F. M. Bailey Plants Source Classification	Parasite
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-17035R

Doramectin (Standard)	Structural Classification Microorganisms Antibiotics Anti-parasitic Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Parasite Antibiotic Bacterial
Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .

HY-N2656

5,7,8-Trimethoxycoumarin	Zanthoxylum dimorphophyllum Hemsl. Rutaceae Coumarins Phenylpropanoids Plants	Parasite
5,7,8-Trimethoxycoumarin is an anti-parasite agent with IC₅₀s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively .

HY-W071746R

Linolelaidic acid (Standard) Linoelaidic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Parasite Apoptosis
Linolelaidic acid (Standard) is the analytical standard of Linolelaidic acid. This product is intended for research and analytical applications. Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections[1][2][3].

HY-N11920

Kadsurenin B	Lignans Piperaceae Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi Source Classification	Platelet-activating Factor Receptor (PAFR)
Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc .

HY-129278

Lunarine	Alkaloids Lunaria annua L. Other Alkaloids Plants Brassicaceae Source Classification	Parasite
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD₅₀ of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with K_i of 304 μM .

HY-118495

Cardol diene	Phenols Polyphenols Plants Anacardium occidentaleL. Anacardiaceae Source Classification	Parasite
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-N7141R

Spiramycin I (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Anti-parasitic Disease Research Source Classification	Reference Standards Antibiotic Parasite Bacterial
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and *antiparasitic* .

HY-50730R

Asparagusic acid (Standard)	Structural Classification Liliaceae Ketones, Aldehydes, Acids Plants Source Classification Asparagus officinalis L.	Parasite Endogenous Metabolite Reference Standards
Asparagusic acid (Standard) is the analytical standard of Asparagusic acid. This product is intended for research and analytical applications. Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-N10402

Norbatzelladine L	Alkaloids Microorganisms Source Classification	Fungal Bacterial Parasite
Norbatzelladine L (Compound 2) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Norbatzelladine L inhibits Pdr5p ATPase activity with an IC₅₀ of 3.8 µM. Norbatzelladine L shows antifungal, *antiparasitic, antiviral, antibacterial* and antitumoral activities .

HY-B0489R

Arecoline hydrobromide (Standard) methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide (Standard)	Alkaloids Structural Classification Areca catechu L. Other Alkaloids Palmae Plants Source Classification	Reference Standards mAChR nAChR
Arecoline hydrobromide (Standard) is the analytical standard of Arecoline hydrobromide. This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-W671129

Frenolicin B	Structural Classification Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
Frenolicin B is a covalent enzyme inhibitor and an orally active antiparasitic agent, with an IC₅₀ of 0.2 μM against human Prx1. Frenolicin B selectively inhibits Glutaredoxin 3 via covalent modification of the active-site cysteines Cys159/Cys261. Frenolicin B selectively inhibits Peroxiredoxin 1 via covalent modification of the active-site cysteines Cys83/Cys173. Frenolicin B can be used in research related to colon cancer, breast cancer, lung cancer and malaria .

HY-125298

Cycloaspeptide A	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Parasite
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has *antiparasitic* activity .

HY-N15734

6-Dehydro-10-gingerol	Zingiber officinale Roscoe Monophenols Phenols Plants Source Classification Zingiberaceae	Parasite
6-Dehydro-10-gingerol is an antiparasitic compound that can be isolated from ginger roots .

HY-N1451R

Betulonic acid (Standard) Betunolic acid (Standard); Liquidambaric acid (Standard); (+)-Betulonic acid (Standard)	Triterpenes Structural Classification other families Terpenoids Plants Source Classification	Reference Standards Parasite HSV
Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N10441

3β-Hydroxy-hop-22(29)-ene	Cnidoscolus spinosus Lundell Triterpenes Terpenoids Euphorbiaceae Plants Source Classification	Parasite
3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent *antiparasitic* agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana .

HY-N13197

6-Methyl-5,6-dihydro-2H-pyran-2-one	Natural Products Microorganisms Source Classification	Antibiotic Bacterial Fungal Parasite
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-N10769

Atanine	Zanthoxylum bungeanum Maxim. Alkaloids Rutaceae Quinoline Alkaloids Plants Source Classification	Parasite
Atanine is an alkaloid with antiparasitic activity. Atanine can be isolated from medicinal plant, Evodia rutaecarpa .

Cat. No.	상품명	Chemical Structure

HY-128554S

N-Desethyl amodiaquine-d5
N-Desethyl amodiaquine-d₅ is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC₅₀ values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively .

HY-B0413S

Fenbendazole-d3

5 Publications Verification

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-B0263S

Thiabendazole-d4
Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent .

HY-128554S1

N-Desethyl amodiaquine-d5 dihydrochloride
N-Desethyl amodiaquine-d₅ dihydrochloride is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC₅₀ values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively .

HY-17596S

Closantel-13C6
Closantel- ¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

HY-17598S

Rafoxanide-13C6
Rafoxanide ¹³C₆ is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent .

HY-109077S

Tigolaner-d4
Tigolaner-d₄ is deuterium labeled Tigolaner. Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity .

HY-B0945S

Nitromide-13C6
Nitromide- ¹³C₆ (3,5-Dinitrobenzamide- ¹³C₆) is the ¹³C-labeled Nitromide (HY-B0945). Nitromide is an anti-parasitic agent .

HY-W765261

Eprinomectin B1a-13C,d3
Eprinomectin B1a- ¹³C,d₃ is the deuterium and ¹³C labeled Eprinomectin B1a (HY-N8483). Eprinomectin B1a is a Eprinomectin (HY-12643) metabolite (an antiparasitic compound) .

HY-123230S1

Trifloxystrobin-d3
Trifloxystrobin-d₃ is the deuterium labeled Trifloxystrobin (HY-123230). Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .

HY-W702966

Ethopabate-d5
Ethopabate-d₅ (Ethyl pabate-d₅) is the deuterium labeled Ethopabate (HY-B2138). Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases .

HY-B1548S

Benznidazole-d7
Benznidazole-d₇ (Benznidazol-d₇; Ro 07-1051-d₇; Ro 71051-d₇) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC₅₀ of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease .

HY-B0740S3

Cyclobenzaprine-d3-1 hydrochloride

Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT₂ receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases

HY-113050SA

2,3-Diphosphoglyceric acid-d3 ammonium

2,3-Diphosphoglyceric acid-d3 ammonium (2,3-DPG-d3 ammonium) is the deuterium labeled 2,3-Diphosphoglyceric acid (HY-113050). 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD) .

HY-136450S

Triclabendazole sulfoxide-d3

Triclabendazole sulfoxide-d₃ is the deuterium labeled Triclabendazole sulfoxide. Triclabendazole sulfoxide (TCBZ-SO) is an orally active ABCG2 inhibitor with antiparasitic activity. Triclabendazole sulfoxide inhibits ABCG2-mediated active efflux and ATPase activity. Triclabendazole sulfoxide increases the intracellular accumulation of Mitoxantrone (HY-13502). Triclabendazole sulfoxide reduces the apical-directed transepithelial transport of Nitrofurantoin and Danofloxacin, while increasing their basolateral-directed transepithelial transport. Triclabendazole sulfoxide elevates the plasma levels of sulfasalazine in wild-type mice. Triclabendazole sulfoxide decreases ABCG2-mediated secretion of Nitrofurantoin into milk in wild-type lactating mice. Triclabendazole sulfoxide can be used in the research of insecticidal agents and cancers such as breast cancer .

HY-136450S1

Triclabendazole sulfoxide-13C,d3

Triclabendazole sulfoxide- ¹³C,d₃ is the ¹³C- and deuterium labeled Triclabendazole sulfoxide. Triclabendazole sulfoxide (TCBZ-SO) is an orally active ABCG2 inhibitor with antiparasitic activity. Triclabendazole sulfoxide inhibits ABCG2-mediated active efflux and ATPase activity. Triclabendazole sulfoxide increases the intracellular accumulation of Mitoxantrone (HY-13502). Triclabendazole sulfoxide reduces the apical-directed transepithelial transport of Nitrofurantoin and Danofloxacin, while increasing their basolateral-directed transepithelial transport. Triclabendazole sulfoxide elevates the plasma levels of sulfasalazine in wild-type mice. Triclabendazole sulfoxide decreases ABCG2-mediated secretion of Nitrofurantoin into milk in wild-type lactating mice. Triclabendazole sulfoxide can be used in the research of insecticidal agents and cancers such as breast cancer .

HY-W739837

Arecoline-d5 hydrobromide
Arecoline-d₅ hydrobromide is the deuterium labeled Arecoline hydrobromide (HY-B0489). Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-W751350

Cyclobenzaprine-d6

Cyclobenzaprine-d₆ is the deuterium labeled Cyclobenzaprine. Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT₂ receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases .

HY-W751808S

2,3-Diphosphoglyceric acid-13C3

2,3-Diphosphoglyceric acid- ¹³C₃ is the ¹³C-labeled 2,3-Diphosphoglyceric acid (HY-113050). 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD) .

HY-N0176S6

Dihydroartemisinin-d

Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

Cat. No.	상품명		Classification

HY-174604

Human IL4 mRNA		mRNA Interleukin & Receptors
Human IL4 mRNA encodes the human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4 mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation.

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