192185-72-1

Tipifarnib Chemical Structure
192185-72-1

Chemical Structure

Tipifarnib

Synonym(s): IND 58359; R115777

  • CAS No.: 192185-72-1
  • Formula:C27H22Cl2N4O
  • Molecular Weight:489.40

IUPAC Name: (R)-6-(amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one

InChIKey: PLHJCIYEEKOWNM-HHHXNRCGSA-N

SMILES: O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)[C@@](N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C

Biological Activity: Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-10502
Tipifarnib 99.72% Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
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HY-10502R
Tipifarnib (Standard) ≥98% Tipifarnib (Standard) is the analytical standard of Tipifarnib (HY-10502). This product is intended for research and analytical applications. Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
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References