117704-25-3
117704-25-3
Chemical Structure
Doramectin
- CAS No.: 117704-25-3
- Formula:C50H74O14
- Molecular Weight:899.11
InChIKey: QLFZZSKTJWDQOS-YDBLARSUSA-N
SMILES: CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]\7(O)[C@@]4([H])C=C(C)[C@H]8O)C1
Biological Activity: Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Doramectin | 98.22% | Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model. | ||||||||||||||||||||
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Doramectin (Standard) | 97.36% | Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-136968epi-Doramectin -
Similarity Score 0.89
HY-134220Doramectin monosaccharide -
Similarity Score 0.89
HY-1381492-epi-Abamectin -
Similarity Score 0.89
HY-15308RAvermectin B1a (Standard) -
Similarity Score 0.89
HY-W10049178,9-Z-Abamectin B1a -
Similarity Score 0.85
HY-W783593Avermectin A1a -
Similarity Score 0.85
HY-122457Δ2,3-Doramectin -
Similarity Score 0.84
HY-125729Ivermectin B1b -
Similarity Score 0.84
HY-126937Ivermectin B1a -
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References
- [1]. Davey RB, Pound JM, Klavons JA, Lohmeyer KH, Freeman JM, Olafson PU. Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion. Exp Appl Acarol. 2012 Apr;56(4):365-74. doi: 10.1007/s10493-012-9525-1. [Content Brief]
- [2]. Wang XJ, Zhang J, Wang JD, Huang SX, Chen YH, Liu CX, Xiang WS. Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069. Chem Biodivers. 2011 Nov;8(11):2117-25. doi: 10.1002/cbdv.201000295. [Content Brief]
- [3]. Gordana Panic, et al. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003962. [Content Brief]
