4 Results for "

BACE1 substrate

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "BACE1 substrate" in MCE Product Catalog:

Cat. No.: HY-P2714
CAS No.: 186142-28-9
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

SEVNLDAEFR is a substrate for BACE1 .
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Cat. No.: HY-P4899
CAS No.: 310427-94-2
Synonyms: RE(EDANS)EVNLDAEFK(DABCYL)R
Target:  

Beta-secretase

Research Areas:  

Neurological Disease

β-Secretase substrate VI, fluorogenic is an EDANS and DABCYL double-labeled peptide,serves as a fluorescent substrate for BACE1(Em=360nm,Ex=528nm). β-Secretase substrate VI, fluorogenic can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .
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Cat. No.: HY-P4919
CAS No.: 1802078-31-4
Target:  

Beta-secretase

Research Areas:  

Others

Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.
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Cat. No.: HY-187367
Research Areas:  

Infection

WJM590 is an orally active antimalarial agent that also exhibits inhibitory activities against renin, cathepsin D, BACE1, and plasmodial aspartic proteases. WJM590 inhibits substrate and protein maturation processing mediated by key proteases of Plasmodium falciparum, arrests asexual blood-stage parasites at the late schizont stage, inhibits merozoite release, and blocks malaria parasite transmission via vectors. WJM590 exerts selective inhibitory activity against multiple Plasmodium species and drug-resistant Plasmodium falciparum strains, and reduces parasitemia in infected mice. WJM590 can be used in malaria-related research .
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