1 Result for "

BAY 866

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BAY 866" in MCE Product Catalog:

Cat. No.: HY-126180
CAS No.: 1836185-18-2
Target:  

MEK

Research Areas:  

Cancer

BAY-866, a sulfamide campound, is an allosteric MEK1 inhibitor with an IC50 of 14 nM. BAY-866 inhibits cell growth of A375 (BRAF) and HCT116 (K-Ras) with IC50s of 13 nM and 277 nM, respectively. BAY-866 inhibits tumor growth in K-Ras-mutated A549 xenograft model .
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