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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
BCAT2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "BCAT2" in MCE Product Catalog:
3
3 Cited Publications
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BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer .
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BAY-252 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50s of 2 μM and 2 μM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used for the research of cancer .
Cat. No.: HY-159730
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ERG245 is a selective amino acid aminotransferase (BCAT1) inhibitor with a human IC50 of 0.5 nM. ERG245 enhances oxidative phosphorylation (OXPHOS) in CD8 + T cells by specifically inhibiting BCAT1 activity, thereby increasing the cytotoxicity of CD8 + T cells. ERG245 shows anti-inflammatory and anti-tumor activities. ERG245 can be used for the researches of cancer anf inflammation, such as colitis and colon cancer .
Cat. No.: HY-RS01403
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BCAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17299
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Bcat2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcat2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23754
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Bcat2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcat2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156965
CAS No.: 2771756-82-0
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BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux). BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism .
Cat. No.: HY-P701339
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCAT2; Branched-chain-amino-acid aminotransferase; mitochondrial; BCAT(m); Placental protein 18; PP18
Cat. No.: HY-P701340
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCAT2; Branched-chain-amino-acid aminotransferase; mitochondrial; BCAT(m); Placental protein 18; PP18
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
