8 Results for "

BMMC

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "BMMC" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-13508
CAS No.: 459168-41-3
Purity:  99.95%
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

JNJ-7777120 is a potent and selective histamine H4 receptor antagonist (Ki=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory .
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1
1 Cited Publications
Cat. No.: HY-B1148
CAS No.: 3759-92-0
Synonyms: Altafur hydrochloride
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Furaltadone hydrochloride is an orally active antibacterial agent that can be used for the study of intestinal Salmonella infections. Furaltadone has in vitro inhibitory effects on Staphylococcus. In addition, Furaltadone shows inhibitory effects on allergic reactions .
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Cat. No.: HY-120149
CAS No.: 35963-37-2
Purity:  98.29%
Inotodiol activates p53 signaling pathway, inhibits MMP-2/9, and exhibits antitumor activity in cancer cell HeLa. Inotodiol inhibits the generation of ROS and exhibits antioxidant and neuroprotective effects. Inotodiol inhibits the activation of MAPK and NF-κB signaling pathway, and exhibits anti-inflammatory activity. Inotodiol inhibits TLR-4 mediated TNF-α production (IC50s in BMMC and BMDM is 0.7 μM and 3.0 μM), inhibits the degranulation in mast cell, exhibits anti-allergic activity. Inotodiol is orally active .
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Cat. No.: HY-W040150
CAS No.: 77058-74-3
Target:  

LXR

24S,25-Epoxycholesterol is an agonist for Liver X Receptor (LXR). 24S,25-Epoxycholesterol exhibits properties in regulating the cholesterol efflux , inhibiting tumor growth against gastric cancer and glioblastoma and inducing apoptosis in BMMC cells .
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Cat. No.: HY-108944
CAS No.: 1404436-51-6
Purity:  99.82%
Target:  

SHP2 SHP1 Phosphatase

Research Areas:  

Inflammation/Immunology

LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 (IC50=5 μM) and SHP2 (IC50=2.5 μM). LYP-IN-1 exhibits highly efficacious cellular activity in T- and mast cells. LYP-IN-1 can be used for the study of autoimmune disorders . LYP-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-W099504
CAS No.: 111-70-6
Synonyms: n-Heptyl alcohol
1-Heptanol (n-Heptyl alcohol) is a linear primary fatty alcohol. 1-Heptanol selectively inhibits the activating phosphorylation of SAPK/JNK and reduces the phosphorylation level of IκB-α. 1-Heptanol increases plasma membrane fluidity, decreases membrane thermal stability, alters the coupling kinetics of STIM1-ORAI1, inhibits the production of ROS and LTC4, and induces the expression of HSP70. 1-Heptanol is used in the fragrance industry due to its pleasant odor .
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Cat. No.: HY-133907
CAS No.: 941580-60-5
Purity:  99.40%
Target:  

PI3K

Research Areas:  

Inflammation/Immunology Cancer

NVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases .
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Cat. No.: HY-13508R
CAS No.: 459168-41-3
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

JNJ-7777120 (Standard) is the analytical standard of JNJ-7777120. This product is intended for research and analytical applications. JNJ-7777120 is a potent and selective histamine H4 receptor antagonist (Ki=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory .
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