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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Brequinar
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Brequinar" in MCE Product Catalog:
38
38 Cited Publications
Synonyms: DUP785; NSC 368390
Research Areas:
Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.
38
38 Cited Publications
Cat. No.: HY-108325A
CAS No.: 96201-88-6
Synonyms: DuP785 sodium; NSC 368390 sodium
Cat. No.: HY-108325R
CAS No.: 96187-53-0
Synonyms: DUP785 (Standard); NSC 368390 (Standard)
Research Areas:
Brequinar (Standard) is the analytical standard of Brequinar. This product is intended for research and analytical applications. Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.
Cat. No.: HY-108325S
Synonyms: DUP785-d3; NSC 368390-d3
Cat. No.: HY-123313
CAS No.: 96201-52-4
Target:
Research Areas:
S-8660 is an orally active and selective inhibitor of dihydroorotate dehydrogenase (DHODH). S-8660 is an analog of Brequinar (HY-108325) and exhibits immunosuppressive activity. When combined with Cyclosporin A (HY-B0579), it enhances the effect of prolonging cardiac allograft survival. S-8660 can be used for research on cardiac transplant rejection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
