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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Brown Norway rats
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Brown Norway rats" in MCE Product Catalog:
13
13 Publications Verification
Cat. No.: HY-117661
CAS No.: 1818389-84-2
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SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease .
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Acrizanib (LHA510) is a small-molecule vascular endothelial growth factor receptor 2 (VEGFR-2, KDR) inhibitor. Acrizanib inhibits the proliferation of BaF3-Tel-KDR cells dependent on VEGFR-2 activity, with an IC50 of 17.4 nM. Acrizanib can be used in research related to choroidal neovascularization and neovascular age-related macular degeneration .
Cat. No.: HY-P99780
CAS No.: 1422268-07-2
Synonyms: BIIB033
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Cat. No.: HY-19720A
CAS No.: 1141934-97-5
Synonyms: ACU-4429 hydrochloride
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Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
Cat. No.: HY-19720
CAS No.: 1141777-14-1
Synonyms: ACU-4429
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Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
Cat. No.: HY-P4371
CAS No.: 177942-21-1
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Cat. No.: HY-110161
CAS No.: 1021912-42-4
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sst2 Receptor agonist-1 is a potent somatostatin receptor subtype 2 (sst2) agonist with a Ki value of 0.025 nM and a cAMP IC50 value of 4.8 nM. sst2 Receptor agonist-1 can inhibit rat growth hormone (GH) secretion and ocular neovascular lesion formation. Antiangiogenic effect .
Cat. No.: HY-109020A
CAS No.: 1637434-72-0
Synonyms: LHA510 hydrochloride
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Acrizanib hydrochloride (LHA510 hydrochloride) is a small-molecule vascular endothelial growth factor receptor 2 (VEGFR-2, KDR) inhibitor. Acrizanib hydrochloride inhibits the proliferation of BaF3-Tel-KDR cells dependent on VEGFR-2 activity, with an IC50 of 17.4 nM. Acrizanib hydrochloride can be used in research related to choroidal neovascularization and neovascular age-related macular degeneration .
Cat. No.: HY-109020R
CAS No.: 1229453-99-9
Synonyms: LHA510 (Standard)
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Acrizanib (Standard) (LHA510 (Standard)) is the analytical standard of Acrizanib (HY-109020). This product is intended for research and analytical applications. Acrizanib (LHA510) is a small-molecule vascular endothelial growth factor receptor 2 (VEGFR-2, KDR) inhibitor. Acrizanib inhibits the proliferation of BaF3-Tel-KDR cells dependent on VEGFR-2 activity, with an IC50 of 17.4 nM. Acrizanib can be used in research related to choroidal neovascularization and neovascular age-related macular degeneration .
Cat. No.: HY-W015405
CAS No.: 19438-61-0
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4-Methylphthalic anhydride is an organic acid anhydride and an immunogen/sensitizer. 4-Methylphthalic anhydride induces the production of specific immunoglobulin E and immunoglobulin G antibodies. 4-Methylphthalic anhydride is used in studies of occupational allergy .
Cat. No.: HY-183455
CAS No.: 86798-59-6
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CI-930 is a selective, orally active phosphodiesterase 3 (PDE3) inhibitor with an IC50 value of 0.0.84 μM. CI-930 exerts positive inotropic and vasodilatory effects by inhibiting cAMP hydrolysis. CI-930 also regulates hemodynamics, inhibits the proliferation of coronary artery smooth muscle cells, and suppresses the proliferation of mouse splenocytes. CI-930 can be used in research related to heart failure, atherosclerosis, and asthma .
Cat. No.: HY-187103
CAS No.: 2241039-80-3
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JAK1-IN-22 is a JAK1-selective inhibitor with an IC50 of 1.84 μM. JAK1-IN-22 exerts no significant inhibitory effect on JAK2 and JAK3. JAK1-IN-22 can be used in the research of JAK1-related diseases such as asthma, alopecia areata, and type 1 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
