2 Results for "

CC930

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CC930" in MCE Product Catalog:

  • Targets Recommended:
12
12 Cited Publications
Cat. No.: HY-15495
CAS No.: 899805-25-5
Purity:  99.87%
Synonyms: CC-930
Target:  

JNK

Research Areas:  

Inflammation/Immunology

Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
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Cat. No.: HY-15495B
CAS No.: 2517855-91-1
Synonyms: (3S)-CC-930 hydrochloride
Research Areas:  

Inflammation/Immunology

(3S)-Tanzisertib (hydrochloride) ((3S)-CC-930 (hydrochloride)) is an orally active JNK inhibitor (IC50 values for JNK1, JNK2, and JNK3 are 61, 7, and 6 nM, respectively). (3S)-Tanzisertib (hydrochloride) selectively inhibits ERK1, p38α, and EGFR (IC50 = 0.48, 3.4, and 0.38 μM, respectively). (3S)-Tanzisertib (hydrochloride) inhibits LPS-induced TNFα production in an acute rat PK-PD model. (3S)-Tanzisertib (hydrochloride) can be used in idiopathic pulmonary fibrosis (IPF) research .
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