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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
CGRP
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "CGRP" in MCE Product Catalog:
45
45 Publications Verification
Synonyms: BIBN-4096; BIBN 4096BS
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Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP .
45
45 Publications Verification
Synonyms: BIBN-4096 hydrochloride; BIBN4096BS hydrochloride
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Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP .
12
12 Cited Publications
Synonyms: BMS-927711; BHV-3000
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Rimegepant (BMS-927711; BHV-3000) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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12 Cited Publications
Cat. No.: HY-15498A
CAS No.: 1374024-48-2
Synonyms: BMS-927711 sulfate hydrate; BHV-3000 sulfate hydrate
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Rimegepant (BMS-927711) sulfate hydrate is a potent, orally active, selective and competitive calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki of 0.027 nM and an IC50 of 0.14 nM for hCGRP receptor. Rimegepant sulfate hydrate can be used for migraine research .
9
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
9
9 Cited Publications
Cat. No.: HY-P0209
CAS No.: 129121-73-9
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9
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
6
6 Cited Publications
Cat. No.: HY-P1071
CAS No.: 90954-53-3
Synonyms: Calcitonin gene-related peptide
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6
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5
5 Cited Publications
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MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC50=0.12 nM; Ki=0.024 nM). MK-3207 can be used for migraine studies .
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5 Cited Publications
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MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
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2
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Telcagepant (MK-0974) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with Kis of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively.
2
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2
2 Cited Publications
Cat. No.: HY-P99019
CAS No.: 1655501-53-3
Synonyms: TEV-48125; LBR-101; PF-04427429; RN-307
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1
1 Cited Publications
Cat. No.: HY-P1548
CAS No.: 101462-82-2
Synonyms: Human β-CGRP; CGRP-II (Human)
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1
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1
1 Cited Publications
Synonyms: Zavegepant; BHV-3500
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Vazegepant (Zavegepant) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist. Vazegepant can be used in the study of migraine .
1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
