2 Results for "

Celastramycin A

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Celastramycin A" in MCE Product Catalog:

Cat. No.: HY-122292
CAS No.: 188988-62-7
Celastramycin A is a potent innate immune suppressor and Antibacterial agent . Celastramycin A inhibits TNF-α-stimulated IL-8 production and reduces IL-6 in a ZFC3H1-independent manner. Celastramycin A inhibits the growth of Pasteurella multocida and Mannheimia haemolytica and modulates the immune system. Celastramycin A can be used for research on bovine respiratory disease (BRD) .
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Cat. No.: HY-N12905
CAS No.: 491600-94-3
Celastramycin A isomer is an isomer of Celastramycin A (HY-122292), an antibiotic against Gram-negative bacteria and Mycobacterium tuberculosis with an MIC of 0.05-3.1 μg/mL. Celastramycin A exerts immunosuppressive effects in Drosophila ex vivo via the immunodeficiency pathway (IC50 of 8 ng/mL), inhibits human innate immune responses via the TNF-α pathway, and inhibits IL-8 production in HUEVC with an IC50 of 60 ng/mL .
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