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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
CerS6
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "CerS6" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-19542
CAS No.: 124753-97-5
Synonyms: C6-Cer; N-Hexanoylsphingosine
C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
Cat. No.: HY-RS29482
Target:
Research Areas:
CERS6 Cattle Pre-designed siRNA Set A is a siRNA containing three designed siRNAs for CERS6 gene (Cattle).
Cat. No.: HY-RS02541
Target:
Research Areas:
CERS6 Human Pre-designed siRNA Set A contains three designed siRNAs for CERS6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-133488
CAS No.: 1402703-50-7
Research Areas:
ST1072 is an inhibitor of CerS4 and CerS6. ST1072 preferentially inhibits CerS6 over CerS4, and reduces the production of C16 ceramide. ST1072 impairs TCR-mediated N-RAS activation, ERK signaling pathway, and the colocalization of CD3/PKCθ. ST1072 decreases the production of IFN-γ as well as the migration of donor cells to target organs. ST1072 regulates immune cell populations and the expression of co-stimulatory molecules. ST1072 can be used in research related to colon cancer, cervical cancer, graft-versus-host disease, and hematologic malignancies .
Cat. No.: HY-119633
CAS No.: 37924-13-3
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Research Areas:
Perfluidone is a selective 3-ketoacyl-CoA synthase (KCS) inhibitor with IC50s of 0.21 and 7.60 μM for CER6 (KCS6) and FAE1 (KCS18), respectively. Perfluidone significantly inhibits very-long-chain fatty acid (VLCFA) synthesis. Perfluidone has phytotoxic activity and inhibits Lemna paucicostata growth. Perfluidone can be uses as a plant growth regulator and herbicide for agriculture research .
Cat. No.: HY-W766368
Synonyms: C6-Cer-13C2,d2; N-Hexanoylsphingosine-13C2,d2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
