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Cholesteryl acetate (Standard)

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W010800R
    Cholesteryl hemisuccinate (Standard)

    		Reference Standards Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis Cancer
    Cholesteryl hemisuccinate (Standard) is the analytical standard of Cholesteryl hemisuccinate. This product is intended for research and analytical applications. Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth[1][2].
    Cholesteryl hemisuccinate (Standard)
  • HY-133962
    Cholesteryl erucate

    		Biochemical Assay Reagents Others
    Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.
    Cholesteryl erucate
  • HY-131389
    Cholesteryl heptadecanoate

    		Biochemical Assay Reagents Others
    Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
    Cholesteryl heptadecanoate
  • HY-113086
    CE(16:1(9Z))

    16:1(9Z) CE; 16:1(9Z) Cholesterol ester; Cholesterol Palmitoleate

    		 Endogenous Metabolite Cardiovascular Disease
    CE(16:1(9Z)) (16:1(9Z) CE) is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE -/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.
    CE(16:1(9Z))
  • HY-W010708R
    Cholesteryl palmitate (Standard)

    		Reference Standards Endogenous Metabolite Inflammation/Immunology
    Cholesteryl palmitate (Standard) is the analytical standard of Cholesteryl palmitate. This product is intended for research and analytical applications. Cholesteryl palmitate is the main cholesterol ester found in human blephariol and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eye syndrome. Cholesteryl palmitate can be used as a predictor of fetal lung maturity. Cholesteryl palmitate can be used as a prognostic biomarker for chronic interstitial pneumonia.
    Cholesteryl palmitate (Standard)
  • HY-107823R
    Cholesteryl acetate (Standard)

    Cholesterol 3-acetate (Standard); Cholesterin acetate (Standard); Cholesterol 3β-acetate (Standard)

    		 Endogenous Metabolite Reference Standards Others
    Cholesteryl acetate (Standard) is the analytical standard of Cholesteryl acetate. This product is intended for research and analytical applications. Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .
    Cholesteryl acetate (Standard)
  • HY-123016
    9(S)-HODE cholesteryl ester

    		Endogenous Metabolite Cardiovascular Disease
    9(S)-HODE cholesteryl ester is originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation.2 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
    9(S)-HODE cholesteryl ester
  • HY-125394
    9(R)-HODE cholesteryl ester

    		Endogenous Metabolite Cardiovascular Disease
    9(R)-HODE cholesteryl ester is originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation.2 9(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
    9(R)-HODE cholesteryl ester
  • HY-14950R
    Dalcetrapib (Standard)

    JTT-705 (Standard); RO4607381 (Standard)

    		 CETP Reference Standards Cardiovascular Disease Cancer
    Dalcetrapib (Standard) is the analytical standard of Dalcetrapib. This product is intended for research and analytical applications. Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
    Dalcetrapib (Standard)
  • HY-W010695R
    Cholesteryl stearate (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Cholesteryl stearate (Standard) is the analytical standard of Cholesteryl stearate (HY-W010695). This product is intended for research and analytical applications. Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.
    Cholesteryl stearate (Standard)
  • HY-W015752R
    5-Methoxyresorcinol (Standard)

    		Reference Standards Drug Intermediate Others
    5-Methoxyresorcinol (Standard) is an analytical standard for 5-Methoxyresorcinol (HY-W015752). This product is intended for research and analytical applications. 5-Methoxyresorcinol is a model molecule for the A ring of flavonoids, specifically mimicking the chemical behavior of the resorcinol-type A ring in catechins. 5-Methoxyresorcinol exhibits very low tocopherol regeneration activity. 5-Methoxyresorcinol shows little inhibition of cholesteryl ester transfer protein (CETP).
    5-Methoxyresorcinol (Standard)
  • HY-107396R
    YM-750 (Standard)

    		Reference Standards Acyltransferase Cardiovascular Disease
    YM-750 (Standard) is the analytical standard of YM-750 (HY-107396). This product is intended for research and analytical applications. YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .
    YM-750 (Standard)
  • HY-100401AR
    Pactimibe sulfate (Standard)

    CS-505 (Standard)

    		 Acyltransferase Reference Standards Cardiovascular Disease
    Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively . Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity .
    Pactimibe sulfate (Standard)

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