Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
DAO
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "DAO" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .
1
1 Cited Publications
Target:
Research Areas:
DAO-IN-2 is a d-amino acid oxidase (DAO) inhibitor (h-DAO IC50 = 245 nM). DAO-IN-2 is a moderate inhibitor of DAAO in vitro and in vivo. DAO-IN-2 can be used to study DAAO-related psychiatric disorders .
1
Target:
Research Areas:
Diamine oxidase (DAO) is an orally active enzyme. Diamine oxidase catalyzes oxidative deamination of various polyamines. Diamine oxidase degrades histamine and polyamines to maintain the metabolic balance of amines in the body. Diamine oxidase is a key regulatory enzyme in rapidly proliferating tissues such as bone marrow and intestinal mucosa. Diamine oxidase can be used in research related to intestinal diseases, small bowel transplant rejection, histamine intolerance, and other conditions .
Cat. No.: HY-W037417
CAS No.: 51856-25-8
Target:
Research Areas:
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors .
Cat. No.: HY-W027382
CAS No.: 67268-37-5
Target:
Research Areas:
SEP-227900 is an orally active and potent DAAO (DAO) inhibitor with potential inhibitory applications. The biological activity of SEP-227900 may show benefits in diseases associated with vitamin D or sunlight exposure. SEP-227900 is expected to play an important role in improving cancer prognosis .
Cat. No.: HY-117292R
CAS No.: 39793-31-2
Research Areas:
DAO-IN-2 (Standard) is the analytical standard of DAO-IN-2 (HY-117292). This product is intended for research and analytical applications. DAO-IN-2 is a novel D-amino acid oxidase (DAO) inhibitor. DAO-IN-2 demonstrates moderate potency for DAO in vitro and ex vivo .
Cat. No.: HY-15913
CAS No.: 83777-30-4
Cat. No.: HY-W026426
CAS No.: 90005-77-9
Target:
Research Areas:
4,5,6,7-Tetrahydro-1,2-benzoxazole-3-carboxylic acid (Compound 244) is an indole compound. 4,5,6,7-Tetrahydro-1,2-benzoxazole-3-carboxylic acid does not inhibit COX-2 and shows the inhibition rate <1% against d-amino acid oxidase (DAO) at 10 μM .
Cat. No.: HY-173255
Target:
Research Areas:
DAO-dBET1 is a Dual-Action-Only PROTAC containing a PROTAC degrader, dBET1 (HY-101838). DAO-dBET1 is a potent BRD4 degrader with a DC50 value of 277 nM in the presence of CoCl2. DAO-dBET1 inhibits hypoxia and Cath-L trigger with an IC50 value of 281 nM .
Cat. No.: HY-RS03523
Target:
Research Areas:
DAO Human Pre-designed siRNA Set A contains three designed siRNAs for DAO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18733
Target:
Research Areas:
Dao Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dao gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23818
Target:
Research Areas:
Aoc1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Aoc1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00771
Target:
Research Areas:
AOC1 Human Pre-designed siRNA Set A contains three designed siRNAs for AOC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25220
Target:
Research Areas:
Dao Rat Pre-designed siRNA Set A contains three designed siRNAs for Dao gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17364
Target:
Research Areas:
Aoc1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aoc1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
