1 Result for "

DC0-NH2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DC0-NH2" in MCE Product Catalog:

Cat. No.: HY-129379
CAS No.: 615538-51-7
Purity:  95.00%
Target:  

ADC Payloads

Research Areas:  

Cancer

DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component .
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