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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
DOPG
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "DOPG" in MCE Product Catalog:
Cat. No.: HY-142980
CAS No.: 62700-69-0
Synonyms: Dioleoylphosphatidylglycerol
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DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .
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3 Cited Publications
Synonyms: Dioleoylphosphatidylglycerol sodium
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .
Cat. No.: HY-170422
CAS No.: 1246303-07-0
Synonyms: Lysyl-DOPG
18:1 Lysyl PG (Lysyl-DOPG) is a cationic phospholipid contains a lysine group and a DOPG. 18:1 Lysyl PG inhibits cationic antimicrobial peptide-induced membrane permeabilization. 18:1 Lysyl PG can be used for the research of infection .
Cat. No.: HY-185588
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Anionic Liposomes (DOPG, 10mM) is a Phosphatidylglycerol (PG)-based-100% DOPG formulation. Anionic Liposomes (DOPG, 10mM) can be used for drug delivery and lipid-protein interactions.
Cat. No.: HY-185587
Anionic Liposomes (DOPG:DOPC (90:10 molar ratio, 10 mM)) is a type of artificial lipid vesicle with strong negative charge (Liposome), composed of 90% DOPG (HY-142980) and 10% DOPC. DOPG is a phosphatidylglycerol composed of unsaturated fatty acids (oleoyl groups), providing negative charges and membrane fluidity. DOPC acts as a neutral matrix lipid, mainly used to maintain the integrity and appropriate fluidity of the lipid bilayer, and does not change the net charge itself.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
