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DPB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcium Channel (1) Cytochrome P450 (1) MMP (1) PKC (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Neurological Disease (3)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121872

DP-b99	MMP Cytochrome P450 Calcium Channel	Neurological Disease
DP-b99 is a blood-brain barrier-permeable inhibitor of CYP2C9 and MMP-9, with a K_i value of 4.655 μM against CYP2C9. DP-b99 inhibits CYP2C9 via apparent non-competitive inhibition, mainly chelates pathological Zn ²⁺ in the membrane environment, attenuates the elevation of intracellular Zn ²⁺ and Ca ²⁺ levels, delays seizure onset and reduces seizure severity, and also prevents MMP-9-dependent dendritic spine remodeling, β-dystroglycan cleavage and gelatinase activity. DP-b99 can be used in the research of acute ischemic stroke, epileptogenesis and stroke .

HY-N16121

12-Deoxyphorbol 13-isobutyrate	PKC	Neurological Disease
12-Deoxyphorbol 13-isobutyrate (ER272) (DPB), a diterpene, is a PKCα activator. 12-Deoxyphorbol 13-isobutyrate can be isolated from Euphorbia resinifera's latex. 12-Deoxyphorbol 13-isobutyrate facilitates neural stem cells (NSCs) proliferation and activation as well as TGFα release in a reaction dependent on PKCα activation. 12-Deoxyphorbol 13-isobutyrate increases cognitive performance and hippocampal neurogenesis in senescence-accelerated mouse-prone (SAMP8) models. 12-Deoxyphorbol 13-isobutyrate can be used for neurodegenerative diseases research .

HY-RS06204

*HLA-DPB1 Human Pre-designed siRNA Set A*	Small Interfering RNA (siRNA)	Others
HLA-DPB1 Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DPB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HLA-DPB1 Human Pre-designed siRNA Set A HLA-DPB1 Human Pre-designed siRNA Set A

HY-121595

5,5-Diphenylbarbituric acid DPB	Others	Neurological Disease
5,5-Diphenylbarbituric acid is an organic compound belonging to the derivatives of barbituric acid. 5,5-Diphenylbarbituric acid can be used for seizure study .

DPBS Buffer (1×)
Dulbecco's phosphate-buffered saline (DPBS) is a balanced salt solution used for a variety of cell culture applications, such as washing cells, diluting cells and preparing reagents. The 500 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16121

12-Deoxyphorbol 13-isobutyrate	Euphorbia triangularis Desf. Terpenoids Diterpenoids Euphorbiaceae Plants Source Classification	PKC
12-Deoxyphorbol 13-isobutyrate (ER272) (DPB), a diterpene, is a PKCα activator. 12-Deoxyphorbol 13-isobutyrate can be isolated from Euphorbia resinifera's latex. 12-Deoxyphorbol 13-isobutyrate facilitates neural stem cells (NSCs) proliferation and activation as well as TGFα release in a reaction dependent on PKCα activation. 12-Deoxyphorbol 13-isobutyrate increases cognitive performance and hippocampal neurogenesis in senescence-accelerated mouse-prone (SAMP8) models. 12-Deoxyphorbol 13-isobutyrate can be used for neurodegenerative diseases research .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71696

	*HLA-DPB1 Protein, Human (His)* HLA class II histocompatibility antigen; HLA class II histocompatibility antigen; DP beta 1 chain; HLA class II histocompatibility antigen; HLA-DP1B; HLA-DPB	Human	E. coli

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Host:	Mouse (6) Rabbit (2)
Reactivity:	Human (8) Rat (4)
Application:	IHC-P (8) ICC/IF (2) IP (2) WB (4) FC (6) ELISA (6)
Isotype:	IgG (2) IgG1 (2) IgG2a (2) IgG2b (2)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (3) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83945

	*HLA-DPB1 Antibody (YA3642)* DPB1; HLA-DP; HLA-DPB; HLA-DP1B	IHC-P, FC, ELISA	Human, Rat
	HLA-DPB1 Antibody (YA3642) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HLA-DPB1.

HY-P83945A

	*HLA-DPB1 Antibody (YA3642)(PBS only)* DPB1; HLA-DP; HLA-DPB; HLA-DP1B	IHC-P, FC, ELISA	Human, Rat
	HLA-DPB1 Antibody (YA3642) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HLA-DPB1.

HY-P83528

	*HLA-DPB1 Antibody (YA3273)* HLA class II histocompatibility antigen; DP beta 1 chain; HLADPB1; HLADP1B; HLADM	WB, IHC-P, ICC/IF, IP	Human
	HLA-DPB1 Antibody (YA3273) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DPB1.

HY-P83528A

	*HLA-DPB1 Antibody (YA3273)(PBS only)* HLA class II histocompatibility antigen; DP beta 1 chain; HLADPB1; HLADP1B; HLADM	WB, IHC-P, ICC/IF, IP	Human
	HLA-DPB1 Antibody (YA3273) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HLA-DPB1.

HY-P84161

	HLA-DPA1 Antibody (YA3858) DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	WB, IHC-P, FC, ELISA	Human
	HLA-DPA1 Antibody (YA3858) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HLA-DPA1.

HY-P84162

	HLA-DPA1 Antibody (YA3859) DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	IHC-P, FC, ELISA	Human, Rat
	HLA-DPA1 Antibody (YA3859) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HLA-DPA1.

HY-P84161A

	HLA-DPA1 Antibody (YA3858)(PBS only) DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	WB, IHC-P, FC, ELISA	Human
	HLA-DPA1 Antibody (YA3858) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HLA-DPA1.

HY-P84162A

	HLA-DPA1 Antibody (YA3859)(PBS only) DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1	IHC-P, FC, ELISA	Human, Rat
	HLA-DPA1 Antibody (YA3859) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HLA-DPA1.

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*HLA-DPB1 Human Pre-designed siRNA Set A*		siRNAs Human Pre-designed siRNA Sets
HLA-DPB1 Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DPB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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