2 Results for "

Deferoxamine-DBCO

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Deferoxamine-DBCO" in MCE Product Catalog:

Cat. No.: HY-158067
CAS No.: 2359695-48-8
Purity:  89.40%
Synonyms: DFO-DBCO
Deferoxamine-DBCO (DFO-DBCO) is a bifunctional small-molecule synthetic building block obtained by covalent conjugation of the DFO metal-chelating group with DBCO, and is a bifunctional chelator. Deferoxamine-DBCO efficiently chelates radioactive metals (such as 89Zr) through the DFO moiety to achieve radiolabeling. Deferoxamine-DBCO undergoes a metal-free Huisgen cycloaddition reaction with azide-containing biomolecules (such as siRNA and monoclonal antibodies) through the DBCO moiety under bioorthogonal conditions to accomplish targeted conjugation. Deferoxamine-DBCO is applicable to research related to bioconjugation chemistry and the preparation of PET radiotracer probes .
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Cat. No.: HY-P11428
CAS No.: 2425606-55-7
Research Areas:  

Others

DBCO-cyclo (RGDfK) is a clickable DBCO-modified cyclic RGD peptide, and also a DBCO derivative of cyclo (RGDfK) (HY-P0023). DBCO-cyclo (RGDfK) is synthesized via an amide coupling reaction between DBCO-NHS ester and cyclo (RGDfK). DBCO-cyclo (RGDfK) can react with azide groups through copper-free click chemistry (SPAAC) to immobilize RGD peptides onto biomaterials or hydrogels. The RGD sequence in DBCO-cyclo (RGDfK) is recognizable by cellular integrins and promotes cell adhesion. DBCO-cyclo (RGDfK) can be used in studies related to tissue engineering, 3D cell culture, and surface functionalization of biomaterials .
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