4 Results for "

Deschloroclozapine

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Deschloroclozapine" in MCE Product Catalog:

88
88 Publications Verification
Cat. No.: HY-42110
CAS No.: 1977-07-7
Target:  

mAChR

Research Areas:  

Neurological Disease

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [ 11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging .
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88
88 Publications Verification
Cat. No.: HY-42110A
Target:  

mAChR

Research Areas:  

Neurological Disease

Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine dihydrochloride binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [ 11C]-Deschloroclozapine dihydrochloride is developed as a promising PET tracer for DREADD imaging .
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1
1 Cited Publications
Cat. No.: HY-P10579
CAS No.: 2225868-19-7
Target:  

Ephrin Receptor

Research Areas:  

Cancer

123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .
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Cat. No.: HY-42110R
CAS No.: 1977-07-7
Research Areas:  

Neurological Disease

Deschloroclozapine (Standard) is the analytical standard of Deschloroclozapine (HY-42110). This product is intended for research and analytical applications. Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist, with blood-brain barrier permeability. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [ 11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging .
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