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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
Diels-Alder reactions
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "Diels-Alder reactions" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W053709A
CAS No.: 1416711-59-5
Synonyms: (4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine (monohydrochloride); Tetrazine-NH2 monohydrochloride
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Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709). Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition . Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Cat. No.: HY-134599
CAS No.: 1580501-97-8
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(2E)-TCO-PNB ester is an active reaction substrate with the properties of trans-cyclooctene derivatives. The core chemical property of (2E)-TCO-PNB ester is its ability to undergo efficient inverse electron-demand Diels-Alder (IEDDA) cycloaddition with tetrazine groups. (2E)-TCO-PNB ester can be used in ligation reactions to verify the integrity of tetrazine groups, and also serves as a key synthetic raw material for the preparation of the prodrug TCO-DOX. (2E)-TCO-PNB ester is applied in research related to drug synthesis and bioorthogonal chemistry .
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TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group .
Cat. No.: HY-136104
Purity: 97.97%
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Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Cat. No.: HY-170704
CAS No.: 1480940-53-1
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DSPE-PEG2000-TCO is a click chemistry coupling partner. DSPE-PEG2000-TCO undergoes a reverse electron-demand Diels-Alder click reaction to form a covalent linkage with tetrazine-modified Cetuximab (HY-P9905). DSPE-PEG2000-TCO maintains the stability of lipid nanoparticles (LNPs) and has high mRNA encapsulation efficiency, which supports cellular uptake and mRNA transfection. DSPE-PEG2000-TCO is used to prepare EGFR-targeted and APN-targeted mRNA-loaded LNPs, mediating receptor-dependent endocytosis, mRNA delivery, and intestinal epithelial transcytosis .
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Tetrazine-PEG4-biotin is a PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Cat. No.: HY-W017831
CAS No.: 25021-08-3
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2-Maleimido acetic acid is a maleimide-containing carboxylic acid ligand used to prepare Pt(IV) complexes capable of undergoing Diels-Alder reaction with furan derivatives for drug targeting and delivery applications .
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Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Cat. No.: HY-157006
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(S)-TCO-PEG3-NH2 is an ADC linker containing 3 PEG units. (S)-TCO-PEG3-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
Cat. No.: HY-151759
CAS No.: 2129525-69-3
Cat. No.: HY-141176
CAS No.: 1799962-26-7
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TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Cat. No.: HY-140731
Purity: 97.12%
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TCO-PEG5000-TCO is a PEG derivative containing an acrylate functional group for drug delivery . TCO-PEG5000-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
