1191901-33-3

TCO-NHS ester Chemical Structure
1191901-33-3

Chemical Structure

TCO-NHS ester

  • CAS No.: 1191901-33-3
  • Formula:C13H17NO5
  • Molecular Weight:267.28

IUPAC Name: (E)-cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate

InChIKey: OUGQJOKGFAIFAQ-OWOJBTEDSA-N

SMILES: O=C(OC1CC/C=C/CCC1)ON2C(CCC2=O)=O

Biological Activity: TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-141165
TCO-NHS ester 97.0% TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References