1191901-33-3
Chemical Structure
TCO-NHS ester
- CAS No.: 1191901-33-3
- Formula:C13H17NO5
- Molecular Weight:267.28
IUPAC Name: (E)-cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate
InChIKey: OUGQJOKGFAIFAQ-OWOJBTEDSA-N
SMILES: O=C(OC1CC/C=C/CCC1)ON2C(CCC2=O)=O
Biological Activity: TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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TCO-NHS ester | 97.0% | TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. | ||||||||||||||||||||
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Keywords