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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
E2F2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "E2F2" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: T417
Target:
Áreas de investigación:
TCRS-417 (T417) is a small-molecular inhibitor for PBX1. TCRS-417 can directly block PBX1-binding to DNA (IC50 = 6.58 μM), and affects PBX1 transcription. TCRS-417 is able to hammer out the stemness traits of Carboplatin (HY-17393)-resistant (CR) cells to revert to a differentiated status through tacking PBX1 signaling cascade. TCRS-417 significantly suppresses self-renewal and proliferation of cancer cells expressing high levels of PBX1. TCRS-417 can decrease the mRNA levels of FOXM1, NEK2, and E2F2 in cancer cell lines. TCRS-417 is selectively toxic against chr1q-amp myeloma and solid tumor cells .
Referencia número: HY-RS04111
Target:
Áreas de investigación:
E2F2 Human Pre-designed siRNA Set A contains three designed siRNAs for E2F2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS19321
Target:
Áreas de investigación:
E2f2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for E2f2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS25812
Target:
Áreas de investigación:
E2f2 Rat Pre-designed siRNA Set A contains three designed siRNAs for E2f2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS23106
Target:
Áreas de investigación:
Mst1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mst1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-E71195
Target:
Áreas de investigación:
15-Hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) acts on prostaglandin E2, F2α and B1, but not on prostaglandin D2.
Referencia número: HY-E71196
Target:
Áreas de investigación:
15-Hydroxyprostaglandin dehydrogenase (NADP+) (EC 1.1.1.197) acts on prostaglandins E2, F2α and B1, but not on prostaglandin D2.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
