2. Search Result
Search Result
Results for "

EBNA1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Peptides

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131236
    EBNA1-IN-SC7

    		EBV Cancer
    EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research [1].
    EBNA1-IN-SC7
  • HY-W725179
    VK-2019

    		EBV Cancer
    VK-2019 is an orally bioavailable selective inhibitor of EBNA1. By binding to the protein-DNA interface to interfere with the recruitment and anchoring of the viral DNA replication machinery, VK-2019 effectively blocks the replication and proliferation of EBV in latently infected cells. VK-2019 reduces the copy number and gene expression level of Epstein-Barr virus in tumor cells, decreases the number of EBER-positive cells, and exhibits significant antiviral, immunomodulatory and antiproliferative activities. VK-2019 successfully inhibits tumor growth in EBV-dependent xenograft models. VK-2019 has favorable systemic exposure and acceptable safety profiles, and is widely used in research on advanced nasopharyngeal carcinoma and various EBV-associated cancers [1] .
    VK-2019
  • HY-125471
    VK-1727
    1 Publications Verification

    		 EBV Infection Inflammation/Immunology Cancer
    VK-1727 is a selective small molecule inhibitor of EBNA1. VK-1727 can reduce EBNA1 DNA binding activity. VK-1727 selectively blocks the proliferation and metabolic activity of EBV+ cells, instead of EBV- cells. VK-1727 is used in multiple sclerosis research [1].
    VK-1727
  • HY-P11299
    EBNA-1 (386–405 aa)

    		EBV Infection Neurological Disease Inflammation/Immunology
    EBNA-1 (386-405 aa) is a cross-reactive viral antigen peptide. EBNA-1 (386-405 aa) has a high molecular similarity to GlialCAM (370-389 aa) and it induces the production of cross-reactive antibodies that recognize both EBV antigens and glial cells in the central nervous system, thereby triggering autoimmune responses. EBNA-1 (386-405 aa) can used for Epstein-Barr virus (EBV) infection and multiple sclerosis (MS) research [1].
    EBNA-1 (386–405 aa)
  • HY-P10772
    L2P4

    		Peptide-Drug Conjugates (PDCs) EBV Cancer
    L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM [1].
    L2P4
  • HY-P10772A
    L2P4 TFA

    		Peptide-Drug Conjugates (PDCs) EBV Cancer
    L2P4 TFA is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 TFA exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM [1].
    L2P4 TFA
  • HY-RS04129
    EBNA1BP2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EBNA1BP2 Human Pre-designed siRNA Set A contains three designed siRNAs for EBNA1BP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EBNA1BP2 Human Pre-designed siRNA Set A
    EBNA1BP2 Human Pre-designed siRNA Set A
  • HY-182246
    MC2050

    		PARP Neurological Disease Inflammation/Immunology Cancer
    MC2050 is a selective PARP-1 inhibitor with an IC50 of 119 nM. MC2050 functionally inhibits PARP-1 activity, including hyperactivation induced by oxidative stress, and reduces the poly (ADP-ribosyl) ation level of histone H1. MC2050 protects neuroblastoma cells from oxidative stress-mediated cell death induced by hydrogen peroxide. MC2050 is applicable to research related to neuroblastoma and Burkitt lymphoma [1].
    MC2050

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: