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Results for "

ELP1 protein

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148772
    PTC258

    		DNA/RNA Synthesis Neurological Disease
    PTC258 is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1). PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model .
    PTC258
  • HY-147149
    BPN-15477

    		DNA/RNA Synthesis Neurological Disease
    BPN-15477 is an orally active, blood-brain barrier-permeable splicing modulator compound (SMC). BPN-15477 restores the correct splicing of exon 20 of the elongator complex protein 1 (ELP1) (EC50 = 1.9 μM), thereby significantly increasing the in vivo functional protein levels in all tissues including the brain. BPN-15477 can be used in the research of familial dysautonomia, such as frontotemporal dementia .
    BPN-15477

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