3 Results for "

ER membrane fluidity

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "ER membrane fluidity" in MCE Product Catalog:

Cat. No.: HY-N16308
CAS No.: 3091879-77-2
Category:  

Lipids

Target:  

Fluorescent Dye

ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes .
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Cat. No.: HY-W067572
CAS No.: 85202-17-1
Synonyms: (-)-Stobadine
Research Areas:  

Cardiovascular Disease

Stobadine is a potent antioxidant and prevents free radical induced alterations in ER membrane fluidity. Stobadine can be used for effective cardio- and neuroprotectants development based on antioxidant or free radical scavenging mechanisms of action .
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Cat. No.: HY-D3107
CAS No.: 1826900-73-5
Target:  

Fluorescent Dye

Research Areas:  

Others

ER-Fluidity is a fluorescent probe used to detect the membrane fluidity of the endoplasmic reticulum (ER). ER-Fluidity consists of BODIPY, Coumarin (HY-N0709) moieties and a long-chain n-octadecyl group (n-C18). The excitation/emission wavelengths of the Coumarin moiety of ER-Fluidity are Ex/Em = 350/439 nm, while those of the BODIPY moiety are Ex/Em = 500/518 nm. In cell experiments, 488 nm is additionally used as an excitation wavelength for the BODIPY moiety .
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