4 Results for "

Emamectin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Emamectin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0837
CAS No.: 155569-91-8
Synonyms: MK-244
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .
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Cat. No.: HY-W765182
Emamectin-d3 is the deuterium labeled Emamectin. Emamectin is a macrocyclic lactone insecticide. Emamectin acts as agonist for GABA-gated chloride channels .
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Cat. No.: HY-130349
CAS No.: 121124-29-6
Synonyms: L-656,748
Target:  

GABA Receptor

Research Areas:  

Infection

Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors α1β1γ2, α1β2γ2, and α1β3γ2 with IC50s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC50=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.
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Cat. No.: HY-125951
CAS No.: 121424-52-0
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Emamectin B1b is a compound of the Avermectin family. Emamectin B1b is one component of Emamectin, accounting for approximately 90% of its content. Emamectin B1b can be used in research on inflammatory skin diseases (including neutrophilic dermatoses) .
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